APOE Protein
Quick Overview for APOE Protein (ABIN935205)
Target
See all APOE ProteinsProtein Type
Origin
Source
Purity
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Sequence
- MKVEQAVETE PEPELRQQTE WQSGQRWELA LGRFWDYLRW VQTLSEQVQE ELLSSQVTQE LRALMDETMK ELKAYKSELE EQLTPVAEET RARLSKELQA AQARLGADME DVRGRLVQYR GEVQAMLGQS TEELRVRLAS HLRKLRKRLL RDADDLQKRL AVYQAGAREG AERGLSAIRE RLGPLVEQGR VRAATVGSLA GQPLQERAQA WGERLRARME EMGSRTRDRL DEVKEQVAEV RAKLEEQAQQ IRLQAEAFQA RLKSWFEPLV EDMQRQWAGL VEKVQAAVGT SAAPVPSDNH
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Characteristics
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Purified recombinant Human ApoE4 protein
Expression System: E.coli -
Endotoxin Level
- < 0.1 ng per µg(1 EU/µg).
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Apolipoprotein E (APOE) (AA 19-311) protein (Fc Tag)
APOE Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Apolipoprotein E (APOE) (AA 19-317) protein (Fc Tag)APOE Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Apolipoprotein E (APOE) (AA 19-311) protein (His tag)APOE Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Apolipoprotein E (APOE) (AA 19-311) protein (His tag)APOE Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Apolipoprotein E (APOE) protein (Myc-DYKDDDDK Tag)APOE Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
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Buffer
- Lyophilized from 20 mM Na3PO4, pH 7.8.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- APOE (Apolipoprotein E (APOE))
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Alternative Name
- ApoE4
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Background
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ApoE4 is the high risk variant of the APOE gene, the gene most associated with increased risk for late-onset Alzheimer's disease. Wikipedia shows that it is not a direct determinant of the disease - at least a third of patients with Alzheimer's disease are ApoE4 negative and some ApoE4 homozygotes never develop the disease. Yet those with ApoE4/ApoE4 have ~20x risk of developing Alzheimer's.
Alternative Names: ApoE 4, ApoE-4, Apolipoprotein E4 protein, ApoE-4 protein, ApoE 4 protein, ApoE4, Apo-A4 protein, Apo E4 protein -
Molecular Weight
- 34.4 kDa
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Pathways
- Regulation of Cell Size, Lipid Metabolism
Target
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