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APOE Protein

APOE Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % pure
Catalog No. ABIN935224
  • Target See all APOE Proteins
    APOE (Apolipoprotein E (APOE))
    Protein Type
    Recombinant
    Origin
    • 9
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 15
    • 13
    • 10
    Escherichia coli (E. coli)
    Sequence
    MKVEQAVETE PEPELRQQTE WQSGQRWELA LGRFWDYLRW VQTLSEQVQE ELLSSQVTQE LRALMDETMK ELKAYKSELE EQLTPVAEET RARLSKELQA AQARLGADME DVRGRLVQYR GEVQAMLGQS TEELRVRLAS HLRKLRKRLL RDADDLQKRL AVYQAGAREG AERGLSAIRE RLGPLVEQGR VRAATVGSLA GQPLQERAQA WGERLRARME EMGSRTRDRL DEVKEQVAEV RAKLEEQAQQ IRLQAEAFQA RLKSWFEPLV EDMQRQWAGL VEKVQAAVGT SAAPVPSDNH
    Characteristics
    Purified recombinant Human ApoE4 protein
    Expression System: E.coli
    Purity
    > 90 % pure
    Endotoxin Level
    < 0.1 ng per µg(1 EU/µg).
    Top Product
    Discover our top product APOE Protein
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
    Buffer
    Lyophilized from 20 mM Na3PO4, pH 7.8.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    APOE (Apolipoprotein E (APOE))
    Alternative Name
    ApoE4 (APOE Products)
    Synonyms
    ad2 Protein, apoprotein Protein, im:7036787 Protein, wu:fb69a05 Protein, zgc:110064 Protein, apoe Protein, AI255918 Protein, AD2 Protein, LDLCQ5 Protein, LPG Protein, APOEA Protein, Apo-E Protein, apolipoprotein E Protein, apolipoprotein Ea Protein, apoe Protein, apoea Protein, Apoe Protein, APOE Protein
    Background
    ApoE4 is the high risk variant of the APOE gene, the gene most associated with increased risk for late-onset Alzheimer's disease. Wikipedia shows that it is not a direct determinant of the disease - at least a third of patients with Alzheimer's disease are ApoE4 negative and some ApoE4 homozygotes never develop the disease. Yet those with ApoE4/ApoE4 have ~20x risk of developing Alzheimer's.
    Alternative Names: Apo E4 protein, Apo-A4 protein, ApoE-4, ApoE 4 protein, ApoE-4 protein, Apolipoprotein E4 protein, ApoE 4, ApoE4
    Molecular Weight
    34.4 kDa
    Pathways
    Regulation of Cell Size, Lipid Metabolism
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