WISP2 Protein
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- Target See all WISP2 Proteins
- WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- MQLCPTPCTC PWPPPRCPLG VPLVLDGCGC CRVCARRLGE PCDQLHVCDA SQGLVCQPGA GPGGRGALCL LAEDDSSCEV NGRLYREGET FQPHCSIRCR CEDGGFTCVP LCSEDVRLPS WDCPHPRRVE VLGKCCPEWV CGQGGGLGTQ PLPAQGPQFS GLVSSLPPGV PCPEWSTAWG PCSTTCGLGM ATRVSNQNRF CRLETQRRLC LSRPCPPSRG RSPQNSAF
- Characteristics
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Purified recombinant Human CTGFL protein
Expression System: E.coli
Bioactivity: The ED50 was determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is between 10-20 ng/mL in the presence of 15 ng/mL of human IGF-II. - Purity
- > 95 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product WISP2 Protein
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WNT1 Inducible Signaling Pathway Protein 2 (WISP2) (AA 24-250) protein (GST tag)
WISP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
WNT1 Inducible Signaling Pathway Protein 2 (WISP2) (AA 24-250) protein (His tag)Crystallography grade WISP2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
WNT1 Inducible Signaling Pathway Protein 2 (WISP2) (AA 24-251) protein (His-SUMO Tag)WISP2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
WNT1 Inducible Signaling Pathway Protein 2 (WISP2) proteinWISP2 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
WNT1 Inducible Signaling Pathway Protein 2 (WISP2) protein (Myc-DYKDDDDK Tag)WISP2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in water to a concentration of 0.1- 1.0 mg/mL. Do not raise to neutral pH.
- Buffer
- Supplied lyophilized with no additives.
- Preservative
- Without preservative
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))
- Alternative Name
- CTGFL (WISP2 Products)
- Synonyms
- MGC84196 Protein, WISP2 Protein, ccn5 Protein, CCN5 Protein, CT58 Protein, CTGF-L Protein, Ccn5 Protein, Crgr4 Protein, Ctgfl Protein, Rcop1 Protein, WNT1 inducible signaling pathway protein 2 Protein, WNT1 inducible signaling pathway protein 2 S homeolog Protein, WISP2 Protein, wisp2.S Protein, wisp2 Protein, Wisp2 Protein
- Background
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CTGFL/WISP-2 is a 24.3 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors.
Alternative Names: WISP2 protein, CCN5 protein, CT-58 protein, Connective Tissue Growth Factor-Like protein protein - Molecular Weight
- 24.3 kDa
- Pathways
- WNT Signaling, Growth Factor Binding
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