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CNTF Protein

CNTF Origin: Human Host: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Catalog No. ABIN935291
  • Target See all CNTF Proteins
    CNTF (Ciliary Neurotrophic Factor (CNTF))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 20
    • 8
    • 4
    • 2
    • 2
    • 2
    Human
    Source
    • 27
    • 3
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Sequence
    AFAEQTPLTL HRRDLCSRSI WLARKIRSDL TALMESYVKH QGLNKNINLD SVDGVPVAST DRWSEMTEAE RLQENLQAYR TFQGMLTKLL EDQRVHFTPT EGDFHQAIHT LMLQVSAFAY QLEELMVLLE QKIPENEADG MPATVGDGGL FEKKLWGLKV LQELSQWTVR SIHDLRVISS HQMGISALES HYGAKDKQM
    Characteristics
    Purified recombinant Human CNTF protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to stimulate proliferation of human TF-1 cells using a concentration range of 25.0-35.0 ng/mL.
    Purity
    > 98 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product CNTF Protein
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 5 M Tris, pH 8.0 to a concentration of 0.1-1.0 mg/mL.
    Buffer
    Lyophilized from 5 mM tris, pH 8.0.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    CNTF (Ciliary Neurotrophic Factor (CNTF))
    Alternative Name
    CNTF (CNTF Products)
    Background
    CNTF is a potent neural factor that was originally characterized as a vital factor for the survival of chick ciliary neurons in vitro. CNTF is also important for the survival of other neural cell types including primary sensory neurons, motor neurons, basal forebrain neurons and type 2 astrocytes. CNTF is highly conserved across species and exhibits cross-species bioactivity.
    Alternative Names: Ciliary Neurotrophic Factor protein
    Molecular Weight
    22.7 kDa
    Pathways
    JAK-STAT Signaling
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