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Epigen Protein

EPGN Origin: Human Host: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Catalog No. ABIN935330
  • Target See all Epigen (EPGN) Proteins
    Epigen (EPGN) (Epithelial Mitogen (EPGN))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 7
    • 1
    Human
    Source
    • 4
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    AVTVTPPITA QQADNIEGPI ALKFSHLCLE DHNSYCINGA CAFHHELEKA ICRCFTGYTG ERCEHLTLTS YA
    Characteristics
    Purified recombinant Human Epigen protein
    Expression System: E.coli
    Bioactivity: Determined by the dose-dependent stimulation of the proliferation of Mouse Balb/3T3 cells. The expected ED50 for this effect is 150-300 ng/mL.
    Purity
    > 98 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product EPGN Protein
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    RT/-20 °C
  • Target
    Epigen (EPGN) (Epithelial Mitogen (EPGN))
    Alternative Name
    Epigen (EPGN Products)
    Background
    Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence. Recombinant human Epigen is a 7.9 kDa monomeric protein, containing 72 amino acid residues, which comprises the EGF homologous portion of the Epigen precursor.
    Alternative Names: EPG protein, Epithelial mitogen protein
    Molecular Weight
    7.9 kDa
    Pathways
    RTK Signaling, EGFR Signaling Pathway
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