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CXCL5 Protein

Recombinant CXCL5 protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN935335

Quick Overview for CXCL5 Protein (ABIN935335)

Target

See all CXCL5 Proteins
CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 15
  • 9
  • 4
Human

Source

  • 21
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 98 % pure
  • Sequence

    AAVLRELRCV CLQTTQGVHP KMISNLQVFA IGPQCSKVEV VASLKNGKEI CLDPEAPFLK KVIQKILDGG NKEN

    Characteristics

    Purified recombinant Human ENA78 protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration of 5.0-10.0 ng/mL.

    Endotoxin Level

    < 0.1 ng per µg (1 EU/µg).
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  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Supplied as a lyophilized powder.

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    RT/-20 °C
  • Target

    CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))

    Alternative Name

    ENA78

    Background

    ENA-78 is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78 is a chemoattractant for neutrophils. The Mouse homolog of ENA-78 is called LIX. The three naturally occurring variants of human ENA-78, ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78 contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR' motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors.
    Alternative Names: ENA-78, ENA-78 protein, ENA 78, ENA 78 protein, Mouse protein, CXCL5 protein, LIX protein, ENA-78 protein, ENA78, Epithelial Neutrophil Activating Peptide-78 protein

    Molecular Weight

    8 kDa

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity
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