CXCL5 Protein

Catalog No. ABIN935336

This Recombinant CXCL5 protein is produced in Escherichia coli (E. coli).

Quick Overview for CXCL5 Protein (ABIN935336)

Target: CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Sequence: LRELRCVCLQ TTQGVHPKMI SNLQVFAIGP QCSKVEVVAS LKNGKEICLD PEAPFLKKVI QKILDGGNKE N

Characteristics: Purified recombinant Human ENA78 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-100.0 ng/mL.

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Target Details

Target: CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))

Alternative Name: ENA78

Background: ENA-78 is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78 is a chemoattractant for neutrophils. The Mouse homolog of ENA-78 is called LIX. The three naturally occurring variants of human ENA-78, ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78 contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR' motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors.
Alternative Names: ENA-78, ENA-78 protein, ENA78, ENA-78 protein, ENA 78, ENA 78 protein, CXCL5 protein, Epithelial Neutrophil Activating Peptide-78 protein

Molecular Weight: 8 kDa

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity