FGF5 Protein
Quick Overview for FGF5 Protein (ABIN935346)
Target
See all FGF5 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- MAWAHGEKRL APKGQPGPAA TDRNPIGSSS RQSSSSAMSS SSASSSPAAS LGSQGSGLEQ SSFQWSPSGR RTGSLYCRVG IGFHLQIYPD GKVNGSHEAN MLSVLEIFAV SQGIVGIRGV FSNKFLAMSK KGKLHASAKF TDDCKFRERF QENSYNTYAS AIHRTEKTGR EWYVALNKRG KAKRGCSPRV KPQHISTHFL PRFKQSEQPE LSFTVTVPEK KNPPSPIKSK IPLSAPRKNT NSVKYRLKFR FG
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Characteristics
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Purified recombinant Human FGF5 protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ? 0.5 ng/mL, corresponding to a specific activity of ? 2 x 10^6 units/mg. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in 2 PBS to a concentration of 0.5-1.0 mg/mL.
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Buffer
- Lyophilized from 2x PBS, pH 7.2.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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- FGF5 (Fibroblast Growth Factor 5 (FGF5))
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Alternative Name
- FGF5
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Background
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FGF5 is a secreted heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF5 binds to FGFR 1c and 2c, and plays a regulatory role in the hair growth cycle.
Alternative Names: FGF-5 protein, Fibroblast Growth Factor-5 protein, FGF 5, FGF 5 protein, Smag-82 protein, FGF-5 protein, FGF5, FGF-5, HBGF-5 protein -
Molecular Weight
- 27.6 kDa
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Target
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