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FGF5 Protein

This Recombinant FGF5 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN935346

Quick Overview for FGF5 Protein (ABIN935346)

Target

See all FGF5 Proteins
FGF5 (Fibroblast Growth Factor 5 (FGF5))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 7
  • 1
  • 1
  • 1
Human

Source

  • 6
  • 3
  • 1
Escherichia coli (E. coli)

Purity

> 95 % pure
  • Sequence

    MAWAHGEKRL APKGQPGPAA TDRNPIGSSS RQSSSSAMSS SSASSSPAAS LGSQGSGLEQ SSFQWSPSGR RTGSLYCRVG IGFHLQIYPD GKVNGSHEAN MLSVLEIFAV SQGIVGIRGV FSNKFLAMSK KGKLHASAKF TDDCKFRERF QENSYNTYAS AIHRTEKTGR EWYVALNKRG KAKRGCSPRV KPQHISTHFL PRFKQSEQPE LSFTVTVPEK KNPPSPIKSK IPLSAPRKNT NSVKYRLKFR FG

    Characteristics

    Purified recombinant Human FGF5 protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ? 0.5 ng/mL, corresponding to a specific activity of ? 2 x 10^6 units/mg.

    Endotoxin Level

    < 0.1 ng per µg (1 EU/µg).
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  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstitute in 2 PBS to a concentration of 0.5-1.0 mg/mL.

    Buffer

    Lyophilized from 2x PBS, pH 7.2.

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    RT/-20 °C
  • Target

    FGF5 (Fibroblast Growth Factor 5 (FGF5))

    Alternative Name

    FGF5

    Background

    FGF5 is a secreted heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF5 binds to FGFR 1c and 2c, and plays a regulatory role in the hair growth cycle.
    Alternative Names: FGF-5 protein, Fibroblast Growth Factor-5 protein, FGF 5, FGF 5 protein, Smag-82 protein, FGF-5 protein, FGF5, FGF-5, HBGF-5 protein

    Molecular Weight

    27.6 kDa

    Pathways

    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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