Filamin-Like Protein (LOC409697)
LOC409697
Origin: Chicken
Host: Chicken
Native
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- Target See all Filamin-Like (LOC409697) products
- Filamin-Like (LOC409697)
- Protein Type
- Native
- Origin
- Chicken
- Source
- Chicken
- Characteristics
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Highly purified Filamin protein
Protein Source: Chicken gizzard
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 250 µL of Laemmli buffer.
- Buffer
- Final solution contains 20 mM Tris/acetate pH 7.6, 20 mM NaCl, 0.0 M EDTA, 0 M DTT, and 20 M NaCl.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
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- Target
- Filamin-Like (LOC409697)
- Alternative Name
- Filamin (LOC409697 Products)
- Background
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Actin-binding protein, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.
Description: Chicken gizzard.
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