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IL-15 Protein

Recombinant IL-15 protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN935479

Quick Overview for IL-15 Protein (ABIN935479)

Target

See all IL-15 (IL15) Proteins
IL-15 (IL15) (Interleukin 15 (IL15))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 28
  • 7
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Mouse

Source

  • 38
  • 10
  • 9
  • 4
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 98 % pure
  • Sequence

    MNWIDVRYDL EKIESLIQSI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VAESGCKECE ELEEKTFTEF LQSFIRIVQM FINTS

    Characteristics

    Purified recombinant Mouse IL15 protein
    Expression System: E.coli
    Bioactivity: The ED50 was determined by the stimulation of the proliferation of Mouse CTLL-2 cells is 2 x 10^5 units/mg.

    Endotoxin Level

    < 0.1 ng per µg (1 EU/µg).
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  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstitute with distilled water to a concentration of 0.5-1.0 g/mL.

    Buffer

    Lyophilized from 10 mM Na3PO4, pH 8.0.

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    RT/-20 °C
  • Target

    IL-15 (IL15) (Interleukin 15 (IL15))

    Alternative Name

    IL15

    Background

    IL15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL2. IL15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells.
    Alternative Names: IL-15 protein, IL15, IL-T protein, IL 15 protein, IL-15 protein, IL-15, Interleukin 15 protein, IL 15

    Molecular Weight

    13.3 kDa

    Pathways

    JAK-STAT Signaling, Glycosaminoglycan Metabolic Process
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