IL-5 Protein

Catalog No. ABIN935494

Recombinant IL-5 protein expressed in Escherichia coli (E. coli).

Quick Overview for IL-5 Protein (ABIN935494)

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Sequence: MIPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES

Characteristics: Purified recombinant Human IL5 protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ? 0.15 ng/mL, corresponding to a specific activity of ? 6.6 x 10^6 units/mg.

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with distilled water to a concentration of 0.1 - 1.0 mg/mL.

Buffer: Lyophilized from 20 mM Na3PO4, pH 7.5.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Target Details

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Alternative Name: IL5

Background: IL5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and Mouse IL5 is cross-species reactive.
Alternative Names: IL 5 protein, Interleukin 5 protein, IL5, EDF protein, IL 5, IL-5, IL-5 protein, BCDFII protein, TRF protein, IL-5 protein

Molecular Weight: 26 kDa

Pathways: JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour