IGFBP2 Protein
Quick Overview for IGFBP2 Protein (ABIN935550)
Target
See all IGFBP2 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- EVLFRCPPCT PERLAACGPP PVAPPAAVAA VAGGARMPCA ELVREPGCGC CSVCARLEGE ACQVYTPRCG QGLRCYPHPG SELPLQALVM GEGTCEKRRD AEYGASPEQV ADNGDDHSEG GLVENHVDST MNMLGGGGSA GRKPLKSGMK ELAVFREKVT EQHRQMGKGG KHHLGLEEPK KLRPPPARTP CQQELDQVLE RISTMRLPDE RGPLEHLYSL HIPNCDKHGL YNLKQCKMSL NGQRGECWCV NPNTGKLIQG APTIRGDPEC HLFYNEQQEA RGVHTQRMQ
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Characteristics
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Purified recombinant Human IGF BP2 protein
Expression System: Hi-5 cells
Bioactivity: Determined by its ability to inhibit IGF-I induced proliferation of FDC-P1 cells. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2) (AA 35-305) protein (His tag)
IGFBP2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2) (AA 36-325) protein (His tag)IGFBP2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2) (AA 33-325) protein (His tag)IGFBP2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2) (AA 1-328) protein (GST tag)IGFBP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2) protein (Fc Tag)IGFBP2 Origin: Mouse Host: HEK-293 Cells Recombinant > (65.9+24.5) % as determined by SDS-PAGE
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Comment
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Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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- IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))
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Alternative Name
- IGF BP2
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Background
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IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP2 is a cysteine-rich secreted protein produced by bone cells, and is most abundant in the brain. IGF-BP2 has been shown to inhibit IGF-II action in human breast and ovarian carcinoma cells.
Alternative Names: IGF BP-2, Insulin-like Growth Factor-Binding Protein 2 protein, IGF BP2, IGF BP 2, IGF BP-2 protein, IGF BP-2 protein, IBP-2 protein, IGF BP 2 protein -
Molecular Weight
- 31.5 kDa
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Pathways
- Myometrial Relaxation and Contraction, Growth Factor Binding, Activated T Cell Proliferation
Target
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