IL17B Protein

Catalog No. ABIN935555

This Recombinant IL17B protein is produced in Escherichia coli (E. coli).

Quick Overview for IL17B Protein (ABIN935555)

Target: IL17B (Interleukin 17B (IL17B))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Sequence: MQPRSPKSKR KGQGRPGPLA PGPHQVPLDL VSRMKPYARM EEYERNIEEM VAQLRNSSEL AQRKCEVNLQ LWMSNKRSLS PWGYSINHDP SRIPVDLPEA RCLCLGCVNP FTMQEDRSMV SVPVFSQVPV RRRLCPPPPR TGPCRQRAVM ETIAVGCTCI F

Characteristics: Purified recombinant Human IL17 B protein
Expression System: E.coli
Bioactivity: Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10ng-100ng. Please Note: Results may vary with PBMC donors.

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Target Details

Target: IL17B (Interleukin 17B (IL17B))

Alternative Name: IL17B

Background: IL17B is a disulfide-linked homodimer of two 161 amino acid polypeptide chains. It belongs to the IL17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL17A through IL17F, are secreted as homodimers. IL17B is expressed by T-cells and has been shown to stimulate release of TNF-alpha and IL1beta from cells of the monocyte lineage.
Alternative Names: NIRF protein, IL20 protein, IL17B, Interleukin 17B protein, ILB-17, ILB-17 protein, ILB 17, IL-17B protein, ILB 17 protein

Molecular Weight: 36.6 kDa