IGFBP7 Protein
Quick Overview for IGFBP7 Protein (ABIN935565)
Target
See all IGFBP7 ProteinsProtein Type
Origin
Source
Purity
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Sequence
- MSSSDTCGPC EPASCPPLPP LGCLLGETRD ACGCCPMCAR GEGEPCGGGG AGRGYCAPGM ECVKSRKRRK GKAGAAAGGP GVSGVCVCKS RYPVCGSDGT TYPSGCQLRA ASQRAESRGE KAITQVSKGT CEQGPSIVTP PKDIWNVTGA QVYLSCEVIG IPTPVLIWNK VKRGHYGVQR TELLPGDRDN LAIQTRGGPE KHEVTGWVLV SPLSKEDAGE YECHASNSQG QASASAKITV VDALHEIPVK KGEGAEL
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Characteristics
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Purified recombinant Human IGF BP7 protein
Expression System: E.coli -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 30-282) protein (His tag)
IGFBP7 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 26-281) protein (His tag)IGFBP7 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 27-282) protein (His tag)IGFBP7 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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- IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
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Alternative Name
- IGF BP7
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Background
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IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF1n a manner that inhibits IGF1nduced differentiation of skeletal myoblasts, without affecting IGF1nduced proliferation.
Alternative Names: IGF binding protein related protein-1 protein, IGF BP 7, IGF BP-7, Mac25 protein, IGF BP-7 protein, IGF BP7, Insulin-like growth factor binding protein-7 protein, IGFBPrP1 protein, IGF BP 7 protein, IBP-7 protein, IGF BP-7 protein -
Molecular Weight
- 26.4 kDa
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Pathways
- Growth Factor Binding
Target
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