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IGFBP7 Protein (AA 27-282) (His tag)

IGFBP7 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN6387352
  • Target See all IGFBP7 Proteins
    IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 27-282
    Origin
    • 15
    • 4
    • 2
    • 2
    Human
    Source
    • 11
    • 9
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This IGFBP7 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MGSSSSDTCG PCEPASCPPL PPLGCLLGET RDACGCCPMC ARGEGEPCGG GGAGRGYCAP GMECVKSRKR RKGKAGAAAG GPGVSGVCVC KSRYPVCGSD GTTYPSGCQL RAASQRAESR GEKAITQVSK GTCEQGPSIV TPPKDIWNVT GAQVYLSCEV IGIPTPVLIW NKVKRGHYGV QRTELLPGDR DNLAIQTRGG PEKHEVTGWV LVSPLSKEDA GEYECHASNS QGQASASAKI TVVDALHEIP VKKGEGAEL
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product IGFBP7 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.2M NaCl, 50 % glycerol, 2  mM DTT, 1  mM EDTA
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
    Alternative Name
    IGFBP7 (IGFBP7 Products)
    Synonyms
    zgc:85888 Protein, AGM Protein, FSTL2 Protein, IBP-7 Protein, IGFBP-7 Protein, IGFBP-7v Protein, IGFBPRP1 Protein, MAC25 Protein, PSF Protein, RAMSVPS Protein, TAF Protein, Fstl2 Protein, Mac25 Protein, insulin like growth factor binding protein 7 Protein, insulin-like growth factor binding protein 7 Protein, IGFBP7 Protein, igfbp7 Protein, Igfbp7 Protein
    Background
    IGFBP7 is a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm Recombinant human IGFBP7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    28.8kDa (279aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_001544
    UniProt
    Q16270
    Pathways
    Growth Factor Binding
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