IL-5 Protein

Catalog No. ABIN935589

This Recombinant IL-5 protein is expressed in Escherichia coli (E. coli).

Quick Overview for IL-5 Protein (ABIN935589)

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Protein Type: Recombinant

Biological Activity: Active

Origin: Mouse

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Sequence: MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG

Characteristics: Purified recombinant Mouse IL5 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is 5 x 10^5units/mg.

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in water to a concentration of 0.1-1.0 mg/mL.

Buffer: Lyophilized from 10 mM Sodium Phosphate, pH 7.5.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Target Details

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Alternative Name: IL5

Background: IL5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and Mouse IL5 is cross-species reactive.
Alternative Names: IL 5 protein, IL 5, IL5, TRF protein, IL-5 protein, Interleukin 5 protein, BCDFII protein, IL-5, IL-5 protein, EDF protein

Molecular Weight: 26.2 kDa

Pathways: JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour