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FGF7 Protein

This Recombinant FGF7 protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN935597

Quick Overview for FGF7 Protein (ABIN935597)

Target

See all FGF7 Proteins
FGF7 (Fibroblast Growth Factor 7 (FGF7))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 16
  • 6
  • 4
  • 3
  • 1
  • 1
  • 1
Human

Source

  • 17
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 95 % pure
  • Sequence

    MCNDMTPEQM ATNVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA MNKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHNG GEMFVALNQK GIPVRGKKTK KEQKTAHFLP MAIT

    Characteristics

    Purified recombinant Human KGF protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by KGF-responsive BaF3 cells is ? 10 ng/mL, corresponding to a specific activity of ? 1 x 10^5 units/mg.

    Endotoxin Level

    < 0.1 ng per µg (1 EU/µg).
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  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstitute in PBS to a concentration of 0.5-1.0 mg/mL.

    Buffer

    Lyophilized from 15 mM Na3PO4 with 0.25 M NaCl, pH7.0.

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    RT/-20 °C
  • Target

    FGF7 (Fibroblast Growth Factor 7 (FGF7))

    Alternative Name

    KGF

    Background

    Keratinocyte Growth Factor (KGF/FGF7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF/FGF7 plays a role in kidney and lung development, angiogenesis, and wound healing.
    Alternative Names: Keratinocyte Growth Factor protein, HBGF-7 protein, Fibroblast Growth Factor-7 protein

    Molecular Weight

    18.9 kDa

    Pathways

    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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