Chemokine (C-C Motif) Ligand 12 (Ccl12) (Active) Protein

Details for Product No. ABIN935672
Protein Name
Origin
Mouse (Murine)
17
Source
Escherichia coli (E. coli)
14
1
1
Protein Type
Recombinant
Biological Activity
Active
Options
Sequence GPDAVSTPVT CCYNVVKQKI HVRKLKSYRR ITSSQCPREA VIFRTILDKE ICADPKEKWV KNSINHLDKT SQTFILEPSC LG
Characteristics Purified recombinant Mouse MCP5 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-50.0 ng/mL.
Purity > 98 % pure
Endotoxin Level < 0.1 ng per µg (1 EU/µg).
Protein Name
Background The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species.
Alternative Names: MCP5, MCP-5, CCL12 protein, MCP-5 protein, MCP 5, Monocyte Chemotactic Protein-5 protein, MCP-5 protein, MCP 5 protein
Molecular Weight 9.3 kDa
Pathways Cellular Response to Molecule of Bacterial Origin
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Buffer Supplied as a lyophilized powder.
Handling Advice Avoid repeated freeze/thaw cycles.
Storage RT/-20 °C
Storage Comment Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.