Neurotrophin 4 Protein (NTF4)

Catalog No. ABIN935682

This Recombinant Neurotrophin 4 protein is expressed in Escherichia coli (E. coli).

Quick Overview for Neurotrophin 4 Protein (NTF4) (ABIN935682)

Target: Neurotrophin 4 (NTF4)

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Sequence: GVSETAPASR RGELAVCDAV SGWVTDRRTA VDLRGREVEV LGEVPAAGGS PLRQYFFETR CKADNAEEGG PGAGGGGCRG VDRRHWVSEC KAKQSYVRAL TADAQGRVGW RWIRIDTACV CTLLSRTGRA

Characteristics: Purified recombinant Human NT4 protein
Expression System: E.coli
Bioactivity: Determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/mL.

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Supplied lyophilized with no additives.

Preservative: Without preservative

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: Neurotrophin 4 (NTF4)

Alternative Name: NT4

Background: NT-4 is a neurotrophic factor structurally related to beta-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and tr kb receptors and promotes the survival of peripheral sensory sympathetic neurons.
Alternative Names: NT-4/NT-5 protein, NT-4, NT-4 protein, NT4, Neurotrophic 4/5 protein, NT4 protein, NT 4 protein, Neurotrophin-4 protein, NT 4

Molecular Weight: 14.0 kDa

Pathways: RTK Signaling