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NRN1 Protein

Recombinant NRN1 protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN935695

Quick Overview for NRN1 Protein (ABIN935695)

Target

See all NRN1 Proteins
NRN1 (Neuritin 1 (NRN1))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 8
  • 3
  • 1
  • 1
Human

Source

  • 8
  • 3
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 98 % pure
  • Sequence

    MAGKCDAVFK GFSDCLLKLG DSMANYPQGL DDKTNIKTVC TYWEDFHSCT VTALTDCQEG AKDMWDKLRK ESKNLNIQGS LFELCGSGN

    Characteristics

    Purified recombinant Human Neuritin protein
    Expression System: E.coli
    Bioactivity: Determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20.0-30.0 ng/mL.

    Endotoxin Level

    < 0.1 ng per µg (1 EU/µg).
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  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Supplied as a lyophilized powder.

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target

    NRN1 (Neuritin 1 (NRN1))

    Alternative Name

    Neuritin

    Background

    Neuritin is a neurotrophic factor, which is expressed in response to induction of neuronal activity by NGF, BDNF, NT3, and other neural stimulators. It is expressed primarily in postmitotic-differentiating neurons of the developing nervous system and in neuronal structures related to synaptic plasticity in the adult nervous system. Neuritin acts as a molecular mediator of neurite outgrowth, neuronal survival, and synaptic maturation.
    Alternative Names: CPG15 protein, NRN1 protein

    Molecular Weight

    9.7 kDa
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