Otoraplin Protein (OTOR)

Catalog No. ABIN935700

This Recombinant Otoraplin protein is expressed in Escherichia coli (E. coli).

Quick Overview for Otoraplin Protein (OTOR) (ABIN935700)

Target: Otoraplin (OTOR)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Sequence: MVHGIFMDRL ASKKLCADDE CVYTISLASA QEDYNAPDCR FINVKKGQQI YVYSKLVKEN GAGEFWAGS VYGDGQDEMG VVGYFPRNLV KEQRVYQEAT KEVPTTDIDF FCE

Characteristics: Purified recombinant Human OTOR protein
Expression System: E.coli

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: Otoraplin (OTOR)

Alternative Name: OTOR

Background: OTOR, also called Otoraplin and MIAL, is a secreted cytokine and a member of the MIA/OTOR family. Members of this family which also includes MIA, MIA2, and TANGO share a Src homology-3 (SH3)-like domain. OTOR is predominantly expressed in the cochlea of the inner-ear and to a lesser extent in fetal brain and in some cartilage tissues. OTOR appears to be involved in early chondrogenesis of the otic capsule, which is required for normal inner ear development and auditory function.
Alternative Names: MIAL protein, Otoraplin protein

Molecular Weight: 12.7 kDa

Pathways: Sensory Perception of Sound, Regulation of Carbohydrate Metabolic Process