Prolactin Protein (PRL)
Quick Overview for Prolactin Protein (PRL) (ABIN935718)
Target
See all Prolactin (PRL) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- MLPICPGGAA RCQVTLRDLF DRAVVLSHYI HNLSSEMFSE FDKRYTHGRG FITKAINSCH TSSLATPEDK EQAQQMNQKD FLSLIVSILR SWNEPLYHLV TEVRGMQEAP EAILSKAVEI EEQTKRLLEG MELIVSQVHP ETKENEIYPV WSGLPSLQMA DEESRLSAYY NLLHCLRRDS HKIDNYLKLL KCRIIHNNNC
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Characteristics
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Purified recombinant Human Prolactin protein
Expression System: E.coli
Bioactivity: Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0 ng/mL. -
Endotoxin Level
- < 0.1 ng per μg (1 EU/μg).
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Prolactin (PRL) (Active) protein
PRL Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Prolactin (PRL) protein (His tag)PRL Origin: Sheep Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Prolactin (PRL) (AA 29-227) protein (Fc Tag)PRL Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Prolactin (PRL) protein (His tag)PRL Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 92 % as determined by SDS-PAGE
Prolactin (PRL) (AA 30-226) protein (His-IF2DI Tag)PRL Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Prolactin (PRL) (AA 30-226) protein (His-IF2DI Tag)PRL Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Prolactin (PRL) (AA 29-227) protein (GST tag)PRL Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Prolactin (PRL) (AA 29-227) protein (Fc Tag,AVI tag,Biotin)PRL Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Comment
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Biological activity: Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0 ng/mL.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with water.
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Buffer
- Lyophilized from 10 mM Na3PO4, pH 8.0, with 50 mM NaCl.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Prolactin (PRL)
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Alternative Name
- Prolactin
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Background
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Prolactin is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, Prolactin plays an immune-regulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes.
Alternative Names: Luterotropic hormone protein, Mammotropin protein, Lutetropin protein -
Molecular Weight
- 23 kDa
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Pathways
- JAK-STAT Signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Protein targeting to Nucleus
Target
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