LTA Protein
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- Target See all LTA Proteins
- LTA (Lymphotoxin-alpha (LTA))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Chemical
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Source
- Escherichia coli (E. coli)
- Sequence
- MLPGVGLTPS AAQTARQHPK MHLAHSTLKP AAHLIGDPSK QNSLLWRANT DRAFLQDGFS LSNNSLLVPT SGIYFVYSQV VFSGKAYSPK ATSSPLYLAH EVQLFSSQYP FHVPLLSSQK MVYPGLQEPW LHSMYHGAAF QLTQGDQLST HTDGIPHLVL SPSTVFFGAF AL
- Characteristics
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Purified recombinant Human TNF beta protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the cytolysis of Mouse L929 cells in the presence of Actinomycin-D is ? 0.05 ng/mL, corresponding to a specific activity of ? 2 x 10^7 units/mg. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product LTA Protein
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Lymphotoxin-alpha (LTA) (Active) protein
LTA Origin: Chemical Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Lymphotoxin-alpha (LTA) (AA 58-205) protein (His-DYKDDDDK-Strep II Tag)LTA Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Lymphotoxin-alpha (LTA) (AA 34-202) protein (His tag)LTA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Lymphotoxin-alpha (LTA) (AA 35-205) protein (His tag)LTA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Lymphotoxin-alpha (LTA) (AA 1-205) protein (GST tag)LTA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Lymphotoxin-alpha (LTA) (AA 106-205) protein (GST tag)LTA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in Water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- Lyophilized from 10 mM Na3PO4, pH 7.0, with 50 mM NaCl.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- LTA (Lymphotoxin-alpha (LTA))
- Alternative Name
- TNF beta (LTA Products)
- Synonyms
- LT Protein, TNFB Protein, TNFSF1 Protein, LT-[a] Protein, LT-alpha Protein, LT[a] Protein, LTalpha Protein, Ltx Protein, TNF-beta Protein, Tnfb Protein, Tnfsf1b Protein, hlb382 Protein, lymphotoxin alpha Protein, lymphotoxin A Protein, LTA Protein, Lta Protein
- Target Type
- Chemical
- Background
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TNF-beta is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands and signals through TNFR1 and TNFR2. TNF-beta is produced by activated T and B lymphocytes, and has similar activities to TNF-alpha. Like TNF-alpha, TNF-beta is involved in the regulation of various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-beta is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-beta, which effectively anchors the TNF-beta to the cell surface. TNF-beta is cytotoxic to a wide range of tumor cells.
Alternative Names: LT-alpha protein, TNFSF1 protein, TNF-b protein, Tumor Necrosis Factor-beta protein, TNF-beta protein, Lymphotoxin-alpha protein, TNFb protein - Molecular Weight
- 18.6 kDa
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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