VEGFD Protein
Quick Overview for VEGFD Protein (ABIN935904)
Target
See all VEGFD (Figf) ProteinsProtein Type
Origin
Source
Purity
-
-
Sequence
- FAATFYDIET LKVIDEEWQR TQCSPRETCV EVASELGKST NTFFKPPCVN VFRCGGCCNE ESLICMNTST SYISKQLFEI SVPLTSVPEL VPVKVANHTG CKCLPTAPRH PYSIIRR
-
Characteristics
-
Purified recombinant Human VEGF D protein
Expression System: 293 cells -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) protein (His tag)
Figf Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) (AA 1-354) protein (GST tag)Figf Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) (AA 89-205), (full length) protein (GST tag)Figf Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) (AA 93-201) (Active) protein (His tag)Figf Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Buffer
- Supplied as a lyophilized powder.
-
Handling Advice
- Avoid repeated freeze/thaw cycles.
-
Storage
- 4 °C/-20 °C
-
Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
-
-
- VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))
-
Alternative Name
- VEGF D
-
Background
-
VEGF-D, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-D is highly expressed in the lung, heart, small intestine and fetal lung, and at lower levels in the skeletal muscle, colon, and pancreas. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-D may play a role in the formation of the venous and lymphatic vascular systems. It also participates in the growth and maintenance of differentiated lymphatic endothelium in adults. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis.
Alternative Names: FIGF protein, Vascular Endothelial Growth Factor-D protein -
Pathways
- RTK Signaling
Target
-
