CD152 Mulg Protein
Quick Overview for CD152 Mulg Protein (ABIN935913)
Target
Protein Type
Origin
Source
Application
Purity
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Characteristics
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Purified recombinant Human CD152 Mulg Fusion protein
Expression System: BHK cells
Contaminants: Less than 1 % Bovine Immunoglobulin. -
Purification
- Protein A chromatography
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Sterility
- Sterile filtered
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Application Notes
- FC: 0.5 µg/mL
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Comment
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The CD152 Ig fusion protein has biological activity and binds with high affinity to human or mouse CD80 and CD86. CD152 Ig will block the binding of anti-CD80 and anti-CD86 monoclonal antibodies.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
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50 mM Na3PO4 pH 7.5, with 100 mM KCl, and 150 mM NaCl. No preservatives added. Product was sterile filtered under aseptic conditions.
Contaminants: Less than 1 % Bovine Immunoglobulin. -
Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
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Open under aseptic sconditions.
Do not freeze. -
Storage
- 4 °C
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Storage Comment
- Store at 4 °C.
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- CD152 Mulg
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Sub Type
- Fusionprotein
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Background
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Human CD152 is a cell surface glycoprotein expressed at low levels on activated T cells. CD152 is a high affinity receptor for the costimulatory molecules CD80 (B7-1) and CD86 (B7-2) and appears to function as a negative regulator of T cell activation. Therefore, CD152 may be an important player in down regulating T cell mediated immune responses.
Alternative Names: CD 152 protein, CD152, CD 152, CD-152, CD-152 protein -
Molecular Weight
- 110 kDa
Target
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