IL17F Protein
Quick Overview for IL17F Protein (ABIN988050)
Target
See all IL17F ProteinsBiological Activity
Origin
Source
Purity
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Sequence
- MRKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHV
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Characteristics
- Fully biologically active when compared to standard. The ED50 determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 15 ng/ml, corresponding to a specific activity of >, 6.7 × 104 IU/mg.
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Endotoxin Level
- Level Less than 1EU/µg of rHuIL-17F as determined by LAL method
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Interleukin 17F (IL17F) (AA 31-163) (Active) protein (Biotin,His-Avi Tag)
IL17F Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 17F (IL17F) (AA 29-161) (Active) protein (His-Avi Tag)IL17F Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 17F (IL17F) (AA 29-161) (Active) protein (Biotin,His-Avi Tag)IL17F Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 17F (IL17F) (AA 31-163) (Active) protein (His tag)IL17F Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 17F (IL17F) (AA 31-163) (Active) protein (His tag)IL17F Origin: Cynomolgus Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 17F (IL17F) (AA 31-163) (Active) protein (His tag)IL17F Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 17F (IL17F) protein (His tag)IL17F Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Interleukin 17F (IL17F) (AA 28-161) protein (His tag)IL17F Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Interleukin 17F (IL17F) (AA 1-163) protein (GST tag)IL17F Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 17F (IL17F) (Active) protein (His tag)IL17F Origin: Rat Host: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 4 mM HCl to a concentration of 0.1mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
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Storage
- 4 °C
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- IL17F (Interleukin 17F (IL17F))
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Alternative Name
- Interleukin-17F (IL-17F)
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Background
- Human IL-17F is synthesized as a 153 aa precursor with a 20 aa signal sequence and a 133 aa mature region. Like IL-17A, IL-17F contains one potential site for N-linked glycosylation. IL-17A and IL-17F share 50% aa sequence identity. IL17-F homodimer is produced by an activated subset of CD4+ T cells, termed Th17. IL17-F has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. Synonym: Interleukin-17F (IL-17F), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.
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Molecular Weight
- A disulfide-linked homodimer of 30.1kDa, consisting of two 134 amino acid polypeptide chains.
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
Target
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