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CXCL5 Protein

CXCL5 Origin: Mouse Host: Escherichia coli (E. coli) > 97 % by SDS-PAGE and HPLC analyses. Active
Catalog No. ABIN988115
  • Target See all CXCL5 Proteins
    CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))
    Biological Activity
    Active
    Origin
    • 15
    • 8
    • 4
    Mouse
    Source
    • 20
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    APSSVIAATE LRCVCLTVTP KINPKLIANL EVIPAGPQCP TVEVIAKLKN QKEVCLDPEA PVIKKIIIQK ILGSDKKKAK RNALAVERTA SV
    Characteristics
    Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human peripheral blood neutrophils is less than 100 ng/ml, corresponding to a specific activity of >, 1.0 × 104 IU/mg.
    Purity
    > 97 % by SDS-PAGE and HPLC analyses.
    Endotoxin Level
    Level Less than 1EU/µg of rMuLIX/CXCL5 as determined by LAL method
    Top Product
    Discover our top product CXCL5 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
    Storage
    4 °C
  • Target
    CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))
    Alternative Name
    LIX/CXCL5 (CXCL5 Products)
    Background
    The mouse homolog of ENA-78 is called LIX. ENA-78/LIX is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78/LIX is a chemoattractant for neutrophils. The three naturally occurring variants of human ENA-78, ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78/LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR' motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Synonym: LIX/CXCL5 (93a.a.), Mouse. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.
    Molecular Weight
    9.8 kDa, a single, non-glycosylated polypeptide chain containing 93 amino acids.
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity
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