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PTH Protein (AA 7-34)

PTH protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN988196

Quick Overview for PTH Protein (AA 7-34) (ABIN988196)

Target

See all PTH Proteins
PTH (Parathyroid Hormone (PTH))

Biological Activity

Active

Origin

  • 20
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Human

Source

  • 21
  • 8
  • 2
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 97 % by SDS-PAGE and HPLC analyses.
  • Protein Characteristics

    AA 7-34

    Sequence

    LMHNLGKHLN SMERVEWLRK KLQDVHN

    Characteristics

    Fully biologically active when compared to standard. The specific activity is determined by UMR106 cell/cAMP method, corresponding to a specific activity of >, 1.0 × 104 IU/mg.

    Endotoxin Level

    Level Less than 1EU/µg of rHuPTH7-34 as determined by LAL method
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

    Storage

    4 °C
  • Target

    PTH (Parathyroid Hormone (PTH))

    Alternative Name

    Parathyroid Hormone( PTH)

    Target Type

    Hormone

    Background

    Polypeptide hormones secreted by the parathyroid glands, which promote release of calcium from bone to extracellular fluid by activating osteoblasts and inhibiting osteoclasts, indirectly promote increased intestinal absorption of calcium, and promote renal tubular reabsorption of calcium and increased renal excretion of phosphates. It is a major regulator of bone metabolism. Secretion of parathyroid hormone increases when the level of calcium in the extracellular fluid is low. Its action is opposed by calcitonin. Synonym: Parathyroid Hormone 7-34 ( PTH 7-34 ) , Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS,pH7.4.

    Molecular Weight

    3380 Da, a single non-glycosylated polypeptide chain containing 28 amino acids.

    Pathways

    cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
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