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KIT Ligand Protein (KITLG)

KIT Ligand protein expressed in Yeast (Pichia pastoris).
Catalog No. ABIN988245

Quick Overview for KIT Ligand Protein (KITLG) (ABIN988245)

Target

See all KIT Ligand (KITLG) Proteins
KIT Ligand (KITLG)

Biological Activity

Active

Origin

  • 27
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Human

Source

  • 37
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Yeast (Pichia pastoris)

Purity

> 95 % by SDS-PAGE
  • Sequence

    MEGICRNRVT NNVKDVTKLV ANLPKDYMIT LKYVPGMDVL PSHCWISEMV VQLSDSLTDL LDKFSNISEG LSNYSIIDKL VNIVDDLVEC VKENSSKDLK KSFKSPEPRL FTPEEFFRIF NRSIDAFKDF VVASETSDCV VSSTLSPEKD SRVSVTKPFM LPPVanalys is The sequence of the first five N-terminal amino acids has been found to be Met-Glu-Gly-Ile-Cys

    Characteristics

    The ED50, as determined by the dose-dependant stimulation of human TF-1 cells, is < 2 ng/ml, corresponding to a specific activity of 5×105 IU/mg.

    Endotoxin Level

    level is less than 0.1 ng per myg (1 EU/myg) of human SC
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Storage

    -20 °C
  • Target

    KIT Ligand (KITLG)

    Alternative Name

    Stem Cell Factor (SCF)

    Background

    SCF is a hematopoietic growth factor that exerts its activity during the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors.SCF, P. Pichia Derived, human, is a single, glycosylated polypeptide chain containing 165 amino acids and having a molecular mass of ~20 KDa. Synonym: Stem Cell Factor (SCF), human 7. Formulation: Lyophilized from 10 mM Acetic acid.

    Molecular Weight

    ~20 KDa

    Pathways

    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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