Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PSMD4/ASF Products

(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))

Categories

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21. [provided by RefSeq, Jul 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured PSMD4/ASF Categories

PSMD4/ASF Antibodies

High quality antibodies with extensive validation data.

PSMD4/ASF ELISA Kits

Reliable ELISA kits for a wide range of species.

PSMD4/ASF Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PSMD4/ASF Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (5)
Cat. No. ABIN3021330
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7142212
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN519398
Quantity 100 μg
Datasheet Datasheet

Recommended PSMD4/ASF ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969691
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975602
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN778103
Quantity 96 tests
Datasheet Datasheet

Recommended PSMD4/ASF Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316639
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316641
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1343997
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PSMD4/ASF products

Kuzina, Kudriaeva, Smirnov, Dubina, Gabibov, Belogurov: "Glatiramer acetate and nanny proteins restrict access of the multiple sclerosis autoantigen myelin basic protein to the 26S proteasome." in: BioMed research international, Vol. 2014, pp. 926394, (2014) (PubMed).

Elangovan, Oh, Sukumaran, Wójcik, Yoo: "Functional differences between two major ubiquitin receptors in the proteasome; S5a and hRpn13." in: Biochemical and biophysical research communications, Vol. 396, Issue 2, pp. 425-8, (2010) (PubMed).

Safadi, Shaw: "Differential interaction of the E3 ligase parkin with the proteasomal subunit S5a and the endocytic protein Eps15." in: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 1424-34, (2010) (PubMed).

Zhang, Wang, Ehlinger, Randles, Lary, Kang, Haririnia, Storaska, Cole, Fushman, Walters: "Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13." in: Molecular cell, Vol. 35, Issue 3, pp. 280-90, (2009) (PubMed).

Kim, Kim, Uchiki, Gygi, Goldberg: "S5a promotes protein degradation by blocking synthesis of nondegradable forked ubiquitin chains." in: The EMBO journal, Vol. 28, Issue 13, pp. 1867-77, (2009) (PubMed).

Gaurnier-Hausser, Tuszynski: "The immunomodulatory role of angiocidin, a novel angiogenesis inhibitor." in: Current pharmaceutical design, Vol. 15, Issue 17, pp. 1937-48, (2009) (PubMed).

Ghi, Di Brisco, Dallorto, Osella, Orsetti: "Age-related modifications of egr1 expression and ubiquitin-proteasome components in pet dog hippocampus." in: Mechanisms of ageing and development, Vol. 130, Issue 5, pp. 320-7, (2009) (PubMed).

Walters, Kleijnen, Goh, Wagner, Howley: "Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a." in: Biochemistry, Vol. 41, Issue 6, pp. 1767-77, (2002) (PubMed).

Tanahashi, Murakami, Minami, Shimbara, Hendil, Tanaka: "Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis." in: The Journal of biological chemistry, Vol. 275, Issue 19, pp. 14336-45, (2000) (PubMed).

Kawahara, Kasahara, Nishiyama, Ohsumi, Goto, Kishimoto, Saeki, Yokosawa, Shimbara, Murata, Chiba, Suzuki, Tanaka: "Developmentally regulated, alternative splicing of the Rpn10 gene generates multiple forms of 26S proteasomes." in: The EMBO journal, Vol. 19, Issue 15, pp. 4144-53, (2000) (PubMed).

Synonyms and alternative names related to PSMD4/ASF

proteasome 26S subunit, non-ATPase 4 (psmd4), proteasome 26S subunit, non-ATPase 4 (PSMD4), 26S proteasome non-ATPase regulatory subunit 4 (LOC100194679), 26S proteasome non-ATPase regulatory subunit 4 (psmD4), 26S proteasome non-ATPase regulatory subunit 4 (LOC100283637), 26s proteasome non-atpase regulatory subunit 4 (26s proteasomeregulatory subunit s5a) (Smp_000740.1), proteasome 26S subunit, non-ATPase 4 L homeolog (psmd4.L), proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 (Psmd4), proteasome 26S subunit, non-ATPase 4 (Psmd4), proteasome 26S subunit, non-ATPase 4b (psmd4b), AF, af-1, AF-1, Af1, angiocidin, ASF, DDBDRAFT_0202512, DDBDRAFT_0232981, DDB_0202512, DDB_0232981, im:6912672, mcb1, MCB1, Mcb1, PSMD4, psmd4, pub-r5, pUB-R5, rpn10, Rpn10, S5A, wu:fc68c04, xrpn10c, zgc:110247

Protein level used designations for PSMD4/ASF

  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
  • anti-secretory factor
  • 26S proteasome non-ATPase regulatory subunit 4
  • 26S proteasome subunit
  • 26S proteasome regulatory subunit S5A
  • type A von Willebrand factor domain-containing protein
  • ubiquitin interacting motif domain-containing protein
  • proteasome 26S subunit, non-ATPase, 4
  • RPN10 homolog
  • S5a/antisecretory factor protein
  • angiocidin
  • antisecretory factor 1
  • multiubiquitin chain-binding protein
  • proteasome 26S subunit non-ATPase 4
  • 26S proteasome regulatory subunit RPN10
  • proteasome 26S non-ATPase subunit 4
  • anti secretory factor 1
  • multiubiquitin-chain-binding protein
  • antisecretory factor
  • psmd4l
You are here:
Support