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PTPN13 Proteins

(Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Oct 2008].

3 results

PTPN13 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7419421
 
PTPN13 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7419424
 
PTPN13 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7419427
 
  • Type Protein
    • Protein
  • Application
    • Immunogen (Imm)
    • Positive Control (PC)
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Host
    • Escherichia coli (E. coli)
  • Binding Specificity
    • AA 1-161
  • Conjugate
    • His tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
  • Supplier
    • antibodies-online

Aliases for PTPN13 Proteins

protein tyrosine phosphatase, non-receptor type 13 (PTPN13) Proteins
tyrosine-protein phosphatase non-receptor type 13 (LOC100540743) Proteins
protein tyrosine phosphatase, non-receptor type 13 (ptpn13) Proteins
protein tyrosine phosphatase, non-receptor type 13 (Ptpn13) Proteins
AI324989 Proteins
FAP-1 Proteins
hPTP1E Proteins
PNP1 Proteins
ptp Proteins
PTP-BAS Proteins
PTP-BL Proteins
Ptp-bl Proteins
PTP1E Proteins
PTPL1 Proteins
PTPLE Proteins
PTPN13 Proteins
Ptpri Proteins
RIP Proteins
wu:fb50g04 Proteins
zgc:162319 Proteins
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