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QPRT Products

(Quinolinate Phosphoribosyltransferase (QPRT))

Categories

This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq, Jul 2008].

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Featured QPRT Categories

QPRT Antibodies

High quality antibodies with extensive validation data.

QPRT ELISA Kits

Reliable ELISA kits for a wide range of species.

QPRT Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended QPRT Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN565099
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN565098
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN525200
Quantity 50 μg
Datasheet Datasheet

Recommended QPRT ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969810
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969809
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959018
Quantity 96 tests
Datasheet Datasheet

Recommended QPRT Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124728
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317005
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317007
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our QPRT products

Thongon, Zucal, DAgostino, Tebaldi, Ravera, Zamporlini, Piacente, Moschoi, Raffaelli, Quattrone, Nencioni, Peyron, Provenzani: "Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA." in: Cancer & metabolism, Vol. 6, pp. 1, (2018) (PubMed).

Sahm, Oezen, Opitz, Radlwimmer, von Deimling, Ahrendt, Adams, Bode, Guillemin, Wick, Platten: "The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress." in: Cancer research, Vol. 73, Issue 11, pp. 3225-34, (2013) (PubMed).

Hinsch, Frank, Döring, Vorländer, Hansmann: "QPRT: a potential marker for follicular thyroid carcinoma including minimal invasive variant; a gene expression, RNA and immunohistochemical study." in: BMC cancer, Vol. 9, pp. 93, (2009) (PubMed).

Guillemin, Cullen, Lim, Smythe, Garner, Kapoor, Takikawa, Brew: "Characterization of the kynurenine pathway in human neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 47, pp. 12884-92, (2007) (PubMed).

Synonyms and alternative names related to QPRT

quinolinate phosphoribosyltransferase (ECs0113), quinolinate phosphoribosyltransferase (nadC), quinolinate phosphoribosyltransferase (VP2522), nicotinate-nucleotide pyrophosphorylase (STY0167), nicotinate-nucleotide diphosphorylase (nadC), nicotinate-nucleotide diphosphorylase (BJE04_RS13210), carboxylating (nadC), quinolinate phosphoribosyltransferase (QPRT), quinolinate phosphoribosyltransferase (Qprt), 2410027J01Rik, AI647766, ECK0108, JW0105, QPRTase, VF2184

Protein level used designations for QPRT

  • quinolinate phosphoribosyltransferase
  • QAPRTase
  • nicotinate-nucleotide pyrophosphorylase (carboxylating)
  • nicotinate-nucleotide pyrophosphorylase [carboxylating]
  • nicotinate-nucleotide pyrophosphorylase
  • QPRTase
  • quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating))
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