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RAD23B Products

(RAD23 Homolog B (RAD23B))

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The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2011].

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Featured RAD23B Categories

RAD23B Antibodies

High quality antibodies with extensive validation data.

RAD23B ELISA Kits

Reliable ELISA kits for a wide range of species.

RAD23B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RAD23B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (5)
Cat. No. ABIN519601
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN519603
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN6241895
Quantity 100 μL
Datasheet Datasheet

Recommended RAD23B ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959039
Quantity 96 tests
Datasheet Datasheet

Recommended RAD23B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1317279
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317277
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3134493
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RAD23B products

Jones, Moskaluk, Gillenwater, Petroni, Burks, Philips, Rehm, Olazagasti, Kozower, Bao: "Phase I trial of induction histone deacetylase and proteasome inhibition followed by surgery in non-small-cell lung cancer." in: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Vol. 7, Issue 11, pp. 1683-90, (2012) (PubMed).

Chen, Lin, Chow, Lee: "Proteomic identification of Hsp70 as a new Plk1 substrate in arsenic trioxide-induced mitotically arrested cells." in: Proteomics, Vol. 11, Issue 22, pp. 4331-45, (2011) (PubMed).

Crosby, Kulshreshtha, Ivan, Glazer: "MicroRNA regulation of DNA repair gene expression in hypoxic stress." in: Cancer research, Vol. 69, Issue 3, pp. 1221-9, (2009) (PubMed).

Shen, Valencia, Szostak, Szostak, Dong, Liu: "Scanning the human proteome for calmodulin-binding proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 17, pp. 5969-74, (2005) (PubMed).

Huang, Wang, Xu, Lu, Xu, Li, Zhou, Sha: "Expression of a novel RAD23B mRNA splice variant in the human testis." in: Journal of andrology, Vol. 25, Issue 3, pp. 363-8, (2004) (PubMed).

Humphray, Oliver, Hunt, Plumb, Loveland, Howe, Andrews, Searle, Hunt, Scott, Jones, Ainscough, Almeida, Ambrose, Ashwell, Babbage, Babbage, Bagguley, Bailey, Banerjee, Barker, Barlow, Bates, Beasley et al.: "DNA sequence and analysis of human chromosome 9. ..." in: Nature, Vol. 429, Issue 6990, pp. 369-74, (2004) (PubMed).

Mueller, Feigon: "Structural determinants for the binding of ubiquitin-like domains to the proteasome." in: The EMBO journal, Vol. 22, Issue 18, pp. 4634-45, (2003) (PubMed).

Ng, Vermeulen, van der Horst, Bergink, Sugasawa, Vrieling, Hoeijmakers: "A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein." in: Genes & development, Vol. 17, Issue 13, pp. 1630-45, (2003) (PubMed).

Saitoh, Pizzi, Wang: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).

Lee, Li, Tse, Leung, Lee, Tsui, Fung, Lee, Waye: "Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway." in: Life sciences, Vol. 71, Issue 19, pp. 2267-77, (2002) (PubMed).

Synonyms and alternative names related to RAD23B

RAD23 homolog B, nucleotide excision repair protein (RAD23B), RAD23 homolog B, nucleotide excision repair protein (Rad23b), UV excision repair protein RAD23 homolog B (rd23b), RAD23 homolog B, nucleotide excision repair protein (rad23b), RAD23 homolog B, nucleotide excision repair protein S homeolog (rad23b.S), 0610007D13Rik, AV001138, HHR23B, HR23B, MGC107846, mHR23B, P58, p58, zgc:65951

Protein level used designations for RAD23B

  • RAD23, yeast homolog of, B
  • UV excision repair protein RAD23 homolog B
  • XP-C repair complementing complex 58 kDa
  • XP-C repair complementing protein
  • XP-C repair-complementing complex 58 kDa protein
  • RAD23b homolog
  • RAD23 homolog B (S. cerevisiae)
  • RAD23 homolog B
  • HR23B
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