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Retinoblastoma Protein (Rb) Products

(Retinoblastoma Protein (Rb Protein))
Controls the progression of the cell cycle from G1 to S phase. Acts through the modulation of E2F action in response to D- type cyclins. Negative regulator of cell proliferation during leaf and gametophyte development. At later stages of development, restricts the progression through additional endocycles. Regulates the root stem cell pool size. Interaction with mastrevirus RepA or nanovirus Clink protein disrupts the RBR/E2F interaction and releases the transcription of replicative enzymes needed by the virus by increasing the E2F DNA-binding activity.

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Featured Retinoblastoma Protein (Rb) Categories

Retinoblastoma Protein (Rb) Antibodies

High quality antibodies with extensive validation data.

Retinoblastoma Protein (Rb) ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended Retinoblastoma Protein (Rb) Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application FACS, IHC, ELISA, WB
Validations
  • (5)
Cat. No. ABIN3029813
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application DB, IF, IHC, ELISA
Validations
  • (5)
Cat. No. ABIN3029756
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application IF, IHC, ELISA, WB
Validations
  • (5)
Cat. No. ABIN3032465
Quantity 0.4 mL
Datasheet Datasheet

Recommended Retinoblastoma Protein (Rb) ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
  • (1)
Cat. No. ABIN1380692
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380429
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380691
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended Retinoblastoma Protein (Rb) Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7232754
Quantity 35 μg
Datasheet Datasheet

Latest Publications for our Retinoblastoma Protein (Rb) products

Voloboueva, Sun, Xu, Ouyang, Giffard: "Distinct Effects of miR-210 Reduction on Neurogenesis: Increased Neuronal Survival of Inflammation But Reduced Proliferation Associated with Mitochondrial Enhancement." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 37, Issue 11, pp. 3072-3084, (2017) (PubMed).

Barrie, Eno-Amooquaye, Hardcastle, Platt, Richards, Bedford, Workman, Aherne, Mittnacht, Garrett: "High-throughput screening for the identification of small-molecule inhibitors of retinoblastoma protein phosphorylation in cells." in: Analytical biochemistry, Vol. 320, Issue 1, pp. 66-74, (2003) (PubMed).

Markiewicz, Dechat, Foisner, Quinlan, Hutchison: "Lamin A/C binding protein LAP2alpha is required for nuclear anchorage of retinoblastoma protein." in: Molecular biology of the cell, Vol. 13, Issue 12, pp. 4401-13, (2002) (PubMed).

Hogg, Onadim, Baird, Cowell: "Detection of heterozygous mutations in the RB1 gene in retinoblastoma patients using single-strand conformation polymorphism analysis and polymerase chain reaction sequencing." in: Oncogene, Vol. 7, Issue 7, pp. 1445-51, (1992) (PubMed).

McGee, Yandell, Dryja: "Structure and partial genomic sequence of the human retinoblastoma susceptibility gene." in: Gene, Vol. 80, Issue 1, pp. 119-28, (1989) (PubMed).

Friend, Horowitz, Gerber, Wang, Bogenmann, Li, Weinberg: "Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 24, pp. 9059-63, (1988) (PubMed).

Lee, Shew, Hong, Sery, Donoso, Young, Bookstein, Lee: "The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity." in: Nature, Vol. 329, Issue 6140, pp. 642-5, (1987) (PubMed).

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