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CD46 Proteins

(CD46)
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010].

27 results

CD46 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Catalog No. ABIN7274180
$407.42
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
 
CD46 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Catalog No. ABIN7274175
$445.92
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
 
CD46 Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Catalog No. ABIN7274176
$445.92
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
 
CD46 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Catalog No. ABIN6964079
$614.22
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 12 to 15 Business Days
 
CD46 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Catalog No. ABIN1348656
$488.72
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
 
CD46 Origin: Human Host: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, ELISA, Imm, AcA Active
Catalog No. ABIN7678402
$600.74
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 12 to 15 Business Days
 
CD46 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Catalog No. ABIN7122209
$604.62
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
 
CD46 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS
Catalog No. ABIN5854715
$584.62
Plus shipping costs $50.00, if applicable $20.00 dry ice
50 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 18 Business Days
 
CD46 Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Catalog No. ABIN7597359
$212.30
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 12 to 15 Business Days
 
CD46 Origin: Human Host: Wheat germ Recombinant AP
Catalog No. ABIN1329987
$821.85
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
 
CD46 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC
Catalog No. ABIN7393649
$769.83
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
 
CD46 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC
Catalog No. ABIN7404554
$785.85
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
 
CD46 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % pure SDS
Catalog No. ABIN2128446
$1,071.05
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 9 to 12 Business Days
 
CD46 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC
Catalog No. ABIN7403726
$823.91
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
 
CD46 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5709237
$663.30
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 12 Business Days
 
CD46 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Catalog No. ABIN3010673
$857.66
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 20 Business Days
 
CD46 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Catalog No. ABIN3010672
$903.86
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 20 Business Days
 
CD46 Origin: Human Host: Bacteria Recombinant
Catalog No. ABIN7815411
$520.52
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to: United States
Delivery in 7 to 10 Business Days
 
CD46 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713723
$402.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
 
CD46 Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7794640
$596.92
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 2 to 4 Business Days
 
  • Type Protein
    • Protein
  • Application
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Affinity Measurement (AM)
    • Affinity Purification (AP)
    • Immunoassay (IA)
    • Immunoprecipitation (IP)
    • Screening Assay (ScA)
    • Antibody Drug Assay (ADA)
    • Activity Assay (AcA)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Callithrix jacchus
    • Cynomolgus
    • Dog
    • Green Monkey
    • Guinea Pig
    • Pig
    • Saguinus mystax
    • Saguinus oedipus
    • Squirrel Monkey
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Yeast
    • Wheat germ
    • Bacteria
    • Baculovirus infected Insect Cells
    • Mammalian Cells
  • Binding Specificity
    • AA 147-285
    • AA 35-313
    • AA 35-328
    • AA 45-329
    • AA 1-384
    • AA 136-341
    • AA 157-365
    • AA 33-285
    • AA 33-315
    • AA 33-344
    • AA 35-285
    • AA 35-314
    • AA 35-329
    • AA 35-343
    • AA 36-316
    • AA 45-327
    • AA 45-344
    • Extracellular
    • Transcript Variant D
  • Conjugate
    • His tag
    • Un-conjugated
    • Fc Tag
    • His tag,GST tag
    • GST tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
  • Supplier
    • antibodies-online
    • CUSABIO
    • Abbexa
    • Abeomics
    • OriGene
    • ProteoGenix
    • Signalway

Latest Publications for our CD46 Proteins

Baker, Greenshields-Watson, Coughlan, Davies, Uusi-Kerttula, Cole, Rizkallah, Parker: "Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions." in: Nature communications, Vol. 10, Issue 1, pp. 741, (2019) (PubMed).

Stein, Gardner, Hernandez, Kraus, Duty, Ubarretxena-Belandia, Moran, Tortorella: "CD46 facilitates entry and dissemination of human cytomegalovirus." in: Nature communications, Vol. 10, Issue 1, pp. 2699, (2019) (PubMed).

Douradinha, McBurney, Soares de Melo, Smith, Krishna, Barratt-Boyes, Evans, Nascimento, Marques: "C1q binding to dengue virus decreases levels of infection and inflammatory molecules transcription in THP-1 cells." in: Virus research, Vol. 179, pp. 231-4, (2014) (PubMed).

Miyaji, Paul, Shahrizaila, Umapathi, Yuki: "Complement regulatory proteins (CD46, 55 and 59) expressed on Schwann cells: immune targets in demyelinating neuropathies?" in: Journal of neuroimmunology, Vol. 276, Issue 1-2, pp. 172-4, (2014) (PubMed).

Aliases for CD46 Proteins

CD46 molecule (CD46) Proteins
CD46 antigen, complement regulatory protein (Cd46) Proteins
CD46 molecule (Cd46) Proteins
CD46 molecule, complement regulatory protein (CD46) Proteins
membrane cofactor protein-like (LOC100341359) Proteins
membrane cofactor protein-like (LOC103789310) Proteins
AHUS2 Proteins
CD46 Proteins
MCP Proteins
Mcp Proteins
MIC10 Proteins
TLX Proteins
TRA2.10 Proteins
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