Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human Osteopontin Antibodies:
anti-Mouse (Murine) Osteopontin Antibodies:
anti-Rat (Rattus) Osteopontin Antibodies:
Go to our pre-filtered search.
Human Monoclonal Osteopontin Primary Antibody for ICC, IF - ABIN259958
Kon, Yokosaki, Maeda, Segawa, Horikoshi, Tsukagoshi, Rashid, Morimoto, Inobe, Shijubo, Chambers, Uede: Mapping of functional epitopes of osteopontin by monoclonal antibodies raised against defined internal sequences. in Journal of cellular biochemistry 2002
Show all 16 Pubmed References
Human Polyclonal Osteopontin Primary Antibody for ELISA, ICC - ABIN250537
Alonso, Tracey, Ortiz, Pérez-Gómez, Palacios, Pollán, Linares, Serrano, Sáez-Castillo, Sánchez, Pajares, Sánchez-Aguilera, Artiga, Piris, Rodríguez-Peralto: A high-throughput study in melanoma identifies epithelial-mesenchymal transition as a major determinant of metastasis. in Cancer research 2007
Show all 4 Pubmed References
Human Polyclonal Osteopontin Primary Antibody for IHC (fp), IHC - ABIN105163
Ashkar, Weber, Panoutsakopoulou, Sanchirico, Jansson, Zawaideh, Rittling, Denhardt, Glimcher, Cantor: Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. in Science (New York, N.Y.) 2000
Show all 18 Pubmed References
Dog (Canine) Polyclonal Osteopontin Primary Antibody for IHC (p), IP - ABIN5683675
Kim, Shin: Immunohistochemical study of osteopontin in boar testis. in Journal of veterinary science 2007
Show all 4 Pubmed References
Mouse (Murine) Polyclonal Osteopontin Primary Antibody for IF (cc), IF (p) - ABIN723800
Zhang, Men, Fu, Shan, Ye, Wu, Tao, Liu, Jiang: Contribution of SATB2 to the stronger osteogenic potential of bone marrow stromal cells from craniofacial bones. in Cell and tissue research 2012
Show all 3 Pubmed References
Dog (Canine) Polyclonal Osteopontin Primary Antibody for EIA, IHC (p) - ABIN118005
Yamasaki, Nair, Bhattacharya, Yamamoto, Kurazono, Takeda: Cryptic appearance of a new clone of Vibrio cholerae serogroup 01 biotype El Tor in Calcutta, India. in Microbiology and immunology 1997
Show all 14 Pubmed References
Mouse (Murine) Polyclonal Osteopontin Primary Antibody for IHC (p), WB - ABIN3042687
Zhou, Jin, Li, Zhao, Zhang, Wang, Li, Zhang, Xiang: Total flavonoids of Desmodium styracifolium attenuates the formation of hydroxy-L-proline-induced calcium oxalate urolithiasis in rats. in Urolithiasis 2017
Show all 2 Pubmed References
Human Monoclonal Osteopontin Primary Antibody for ICC, IHC - ABIN1098149
Liersch, Gerss, Schliemann, Bayer, Schwöppe, Biermann, Appelmann, Kessler, Löwenberg, Büchner, Hiddemann, Müller-Tidow, Berdel, Mesters: Osteopontin is a prognostic factor for survival of acute myeloid leukemia patients. in Blood 2012
Show all 2 Pubmed References
Human Polyclonal Osteopontin Primary Antibody for IF (p), IHC (p) - ABIN723695
Liu, Zhang, Wang, Zhang, Chen, Wu: A Strontium-Modified Titanium Surface Produced by a New Method and Its Biocompatibility In Vitro. in PLoS ONE 2015
Show all 2 Pubmed References
Dog (Canine) Polyclonal Osteopontin Primary Antibody for ELISA, WB - ABIN2475979
Rangaswami, Bulbule, Kundu: Osteopontin: role in cell signaling and cancer progression. in Trends in cell biology 2006
Respiratory syncytial virus infection leads to increased OPN expression.IL-1beta is involved in the regulation of OPN levels during respiratory syncytial virus infection.
Methylglyoxal-bis (show BAG3 Antibodies)-guanylhydrazone may have potential therapeutic utility in reducing or normalizing OPN levels and regulating monocyte activation in diseases that involve chronic inflammation.
These results might be considered a useful starting point to validate OPN as a prognostic and diagnostic marker of hepatocellular carcinoma.
study demonstrates that the OPN gene SNP rs1126616 is statistically associated with cerebral palsy.
LAMP3 (show CD63 Antibodies) promotes the invasion of osteosarcoma cells via SPP1 signaling.
Extended liver surgery is the only potentially curative treatment for patients with cholangiocarcinoma (CCA (show FBN2 Antibodies)/biliary cancer), but it is currently unclear which patients benefit most from surgery. Detecting serum levels of osteopontin - a specific secreted glycoprotein involved in multiple diseases - in CCA (show FBN2 Antibodies) patients might help to identify those patients that particularly benefit from tumour resection.
MALAT1 could directly bind to miR (show MLXIP Antibodies)-127-5p to inhibit its expression, so as to rescue OPN expression and promote chondrocyte proliferation through PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway.
A linear negative correlation between serum OPN and total bone mineral density (BMD (show BEST1 Antibodies)) of Type I diabetes mellitus patients compared to control group was noticed, indicating that the amount of serum OPN could be effective on BMD (show BEST1 Antibodies) and a good predicting factor for osteoporosis
The epicardial adipose tissue expresses the mRNA of osteopontin, osteoprotegerin (show TNFRSF11B Antibodies), and osteonectin (show SPARC Antibodies) genes that have been implicated in the calcification process; such expression is statistically associated with some components of HDL (show HSD11B1 Antibodies) subclasses in coronary artery disease patients.
OPN regulates CYP7A1 (show CYP7A1 Antibodies) levels and the metabolic fate of liver acetyl-CoA (show LPCAT2 Antibodies) as a result of CHOL and PC metabolism interplay
Study demonstrates that osteopontin has an essential role in modulating macrophage immunological profile and their ability to resist pathogenic forms of amyloid beta-protein.
BSP (show KLK6 Antibodies) and pyrophosphates work in concert to direct mineralization in cementum and likely other mineralized tissues.
OPN deficiency has a protective effect against the progressive lipid deposition and glomerulosclerosis elicited by hypercholesterolemia.
The present study demonstrated that OPN deficiency reduced intestinal absorption of cholesterol by suppressing the expression of NPC1L1 (show NPC1L1 Antibodies), thus protecting mice from cholesterol gallstone formation.
OPN regulates CYP7A1 (show CYP7A1 Antibodies) levels and the metabolic fate of liver acetyl-CoA (show LPCAT1 Antibodies) as a result of CHOL and PC metabolism interplay
These results demonstrate that OPN expressed by fatigue-resistant/slow motor neurons is involved in the second-wave neurodegeneration by up-regulating MMP-9 (show MMP9 Antibodies) through alphavbeta3 integrin in the mouse model of amyotrophic lateral sclerosis.
Osteopontin is highly induced in carbon nanotube-exposed lungs and plays critical roles in TGF-beta1 (show TGFB1 Antibodies) signaling activation and myofibroblast differentiation to promote fibrosis development.
The findings reveal that hepatic OPN contributes to cholesterol gallstone formation by regulating biliary metabolism and might be developed as a therapeutic target for gallstone treatments.
Endogenous OPN emerges as a key player in the pathogenesis of chronic Chagas heart disease, through the upregulation of myocardial CCL5 (show CCL5 Antibodies)/MMP-2 (show MMP2 Antibodies) expression and activities resulting in pro-inflammatory and pro-hypertrophic events, cardiac remodeling and interstitial fibrosis.
In this study, the effect of deficiency of OPN on intestinal tumor development in Apc (show APC Antibodies)-deficient Min mice was investigated.At 16 weeks of age, the number of small intestinal polyps in Min/OPN(+/-) and Min/OPN(-/-) mice was lower than that of Min/OPN(+/+) mice. Colorectal tumor incidences and multiplicities in Min/OPN(+/-) and Min/OPN(-/-) mice were significantly lower than those in Min/OPN(+/+) mice
This implies that a majority of the acidic residues within OPN must be engaged in calcium interaction under physiological conditions.
Genetic variations in the SPP1 promoter affect gene expression and the level of osteopontin secretion into bovine milk.
Osteopontin, osteocalcin and OB-cadherin expression in Synthetic nanohydroxyapatite vs bovine hydroxyapatite cultured Osteoblastic-like cells.
osteopontin (OPN) can serve as a process-directing agent for the intrafibrillar mineralization of collagen.
Results suggest a mechanism of the interaction of UO2(2+) with bone metabolism and a new role for osteopontin (OPN) as a metal transporter.
Upon induction of luteolysis, SPP1 serves as a signaling molecule to recruit or activate immune cells to facilitate luteal regression and tissue degradation.
OPN strongly reduces the amount of biofilm formed in a well-defined laboratory model of acidogenic dental biofilm.
This study demonstrates that adhesion of isolated neonatal rat osteoclasts in vitro was augmented on bovine milk osteopontin (bmOPN) with post-translational modifications (PTMs (show PTMS Antibodies)) compared to human Escherichia-coli-derived recombinant OPN without PTMs (show PTMS Antibodies).
topographical distribution of both the in vivo and in vitro phosphorylation sites of bone sialoprotein (show CRISP1 Antibodies)
the bovine osteopontin gene has two functionally distinct clusters of haplotypes within the QTL region on chromosome 6
These data suggested that methylation in the OPN promoter plays a crucial role in the regulation of OPN expression that we found in cloned pigs genome.
The striking breed differences between hyperprolific Large White and Meishanin pigs of secreted phospoprotein 1 expression in endometrium suggest that SPP1 may be associated with placental efficiency.
Microglia incubated in vitro with different concentrations (0.1 fM-1 nM) of recombinant osteopontin showed increased proliferation at 10 fM.
results of this study reveal faster growth rate and differences in pig productivity according to genotypes of the SPP1 gene
Osteopontin could play an important role in the development of neointimal hyperplasia in venous conduits after coronary artery bypass grafting.
A different MSSCP pattern was shown in osteopontin which indicates that mutation is located in promotor region; the A --> G transitions was identified in two positions -617 and -608
The 3' terminal end of the first intron of porcine SPP1 harbors a C/EBPbeta (show CEBPB Antibodies) binding site and this binding site is negatively affected by the mutant G allele.
in pregnant pigs SPP1 is induced by conceptus estrogen in uterine luminal epithelium and is regulated in a manner coincident with placental progesterone production
osteopontin promotes pathologic mineralization via calcium pyrophosphate dihydrate crystal formation in articular cartilage.
Osteopontin is detected in the majority of germ cells and is involved in spermatogenesis in boar testis.
Infection of urinary tract by Escherichia coli caused higher than normal expression of promoter protein osteopontin and mucosal damage at renal tubular cells.
The SPP1 was principally expressed in motor neurons in lamina IX of the macaque spinal cord.The expression level varied among different spinal segments and correlated positively with neuron size.
results demonstrate that SPP1 is expressed in corticospinal tract neurons in M1 and several other sensorimotor cortices
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.
, early T-lymphocyte activation 1
, osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein
, secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)
, urinary stone protein
, 44 kDa bone phosphoprotein
, bone sialoprotein 1
, calcium oxalate crystal growth inhibitor protein
, early T-lymphocyte activation 1 protein
, osteopontin-like protein
, Sialoprotein (osteopontin)
, bone sialoprotein I
, spp1 protein
, secreted phosphoprotein-1
, LOW QUALITY PROTEIN: osteopontin
, Bone sialoprotein 1