Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
findings show HIV reservoir size is dependent on the presence of a defined NK cell population with a specific transcriptional signature: high NCR (NKp46 and NKp30 (show NCR3 Proteins)) and IFN-gamma (show IFNG Proteins) inducibility upon NCR and cytokine receptor (show EBI3 Proteins) engagement
NKp46 cleavage by Cathepsin G (show CTSG Proteins) severely impairs NKp46-mediated responses of Natural killer cells.
The NKp46 and NKp46-ligand interaction contributes to NK cell activation.
this study shows that the NKp46-activating receptor recognizes an unknown ligand expressed by human metapneumovirus-infected cells
Intrahepatic NKp46 NK cells exhibited anti-HCV activity via cell-to-cell contact. The variation of the NKp46 proportion in individuals could be attributed to the diversity of HCV resistance observed in these individuals.
Taken together, these results demonstrate that endogenous levels of IFN-alpha (show IFNA Proteins) secreted by plasmacytoid dendritic cells induce natural killer cells to lyse HIV-1-infected autologous CD4 (show CD4 Proteins)+ primary T cells via the engagement of NKp46 and NKG2D (show KLRK1 Proteins).
NKp46 was thus involved in the production of serine proteases and interleukin-22 (show IL22 Proteins) in human mast cells.
Age and CMV serostatus influence the expression of NKp30 (show NCR3 Proteins), NKp46 and DNAM-1 (show CD226 Proteins) activating receptors on resting and IL-2 (show IL2 Proteins) activated natural killer cells.
Ncr1-Noe proteins accumulate in the endoplasmic reticulum, and that the expression of Ncr1-Noe proteins, but not WT Ncr1, leads to increased Helios (show ZNFN1A2 Proteins) expression
Data show that regulatory dendritic cells (regDC) restrain IFN-gamma (show IFNG Proteins) secretion by NK cells through secretion of interleukin-10 (IL-10 (show IL10 Proteins)), engagement of MHC class I-specific inhibitory receptors, and the activating receptor NKp46.
this study demonstrates the role of NCR1 in antibody response to mouse cytomegalovirus infection
Our findings uncover a detrimental role of T-bet-dependent NKp46(+) ILCs in the development of CNS autoimmune disease.
The results identify an unexpected phenotypic instability within NKp46(+) ILC3 that suggests a major role for environmental signals in tuning ILC3 functional plasticity.
The authors delineated the fungal ligands to be the Candida glabrata adhesins Epa1, Epa6 (show Epha6 Proteins), and Epa7 and demonstrated that clearance of systemic Candida glabrata infections in vivo depends on their recognition by mouse NCR1.
it is demonstrated that NCR1 dampens allergic eosinophilic airway inflammation.
this study using Ncr1-deficient mice, shows that NCR1 plays a critical role in controlling human metapneumovirus infection
Rag knockout mice that possess fully functional NKp46(+) cells
NK cell receptor (show KLRD1 Proteins) NKp46 regulates graft-versus-host disease.
Ifnar1 (show IFNAR1 Proteins)(-/-) T cells had elevated expression of natural cytotoxicity triggering receptor 1 (NCR1) ligands upon infection, rendering them targets for NCR1 mediated NK cell attack.
has similarity to immunoglobulins\; expressed in NK cells
NK cell-activating receptor
, lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46)
, natural killer cell p46-related protein
, MAR1 (mouse activating receptor 1)
, activating receptor 1
, lymphocyte antigen 94
, NK receptor KILR-1
, lymphocyte antigen 94 homolog (activating NK-receptor
, rat-activating receptor 1