NCR1 Protein (AA 22-254) (His tag,Biotin)
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- Target See all NCR1 Proteins
- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-254
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NCR1 protein is labelled with His tag,Biotin.
- Purpose
- Biotinylated Human NKp46/NCR1/CD335 Protein (Primary Amine Labeling)
- Sequence
- Gln22-Asn254
- Characteristics
- Recombinant Biotinylated Human NKp46/NCR1/CD335 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the N-Terminus.It contains Gln22-Asn254.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Anti-Nkp46 Antibody, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human NKp46, His Tag with the EC50 of 3.1ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product NCR1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
- Alternative Name
- NKp46 (NCR1 Products)
- Synonyms
- CD335 Protein, LY94 Protein, NK-p46 Protein, NKP46 Protein, Ly94 Protein, NKp46 Protein, KILR-1 Protein, Nk-p46 Protein, Nkp46 Protein, natural cytotoxicity triggering receptor 1 Protein, NCR1 Protein, Ncr1 Protein
- Background
- NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells.
- Molecular Weight
- 27.5 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Tris-Bis PAGE result.
- Pathways
- Regulation of Leukocyte Mediated Immunity
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