SH2 Domain Containing 1A Proteins
19 SH2 Domain Containing 1A (SH2D1A) Proteins from 10 manufacturers are available on www.antibodies-online.com.
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19 results:
SH2 Domain Containing 1A (SH2D1A) (AA 1-128) protein (His tag) Protein
SH2 Domain Containing 1A (SH2D1A) (AA 1-126) protein (His tag) Protein
SH2 Domain Containing 1A (SH2D1A) (AA 1-128) protein (His tag) Protein
SH2 Domain Containing 1A (SH2D1A) Protein Protein
SH2 Domain Containing 1A (SH2D1A) (AA 1-128) protein (His tag) Protein
SH2 Domain Containing 1A (SH2D1A) (AA 1-128) protein (GST tag) Protein
SH2 Domain Containing 1A (SH2D1A) (AA 311-391) protein (GST tag) Protein
SH2 Domain Containing 1A (SH2D1A) (AA 18-115) protein (His tag,T7 tag) Protein
SH2 Domain Containing 1A (SH2D1A) (AA 1-128) protein (His tag) Protein
SH2 Domain Containing 1A (SH2D1A) Protein Protein
SH2 Domain Containing 1A (SH2D1A) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein
SH2 Domain Containing 1A (SH2D1A) (AA 1-81), (full length) protein (His tag) Protein
SH2 Domain Containing 1A (SH2D1A) (AA 1-128) protein (His tag) Protein
SH2 Domain Containing 1A (SH2D1A) (AA 2-97) (Active) protein (His tag) Protein
SH2 Domain Containing 1A (SH2D1A) (AA 1-126) protein (His tag) Protein
SH2 Domain Containing 1A (SH2D1A) Protein Profile
Protein Summary
This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative names and synonyms associated with SH2 Domain Containing 1A (SH2D1A)
- SH2 domain containing 1A (SH2D1A) antibody
- SH2 domain containing 1A (Sh2d1a) antibody
- DSHP antibody
- EBVS antibody
- Gm686 antibody
- IMD5 antibody
- LYP antibody
- MTCP1 antibody
- RGD1562408 antibody
- SAP antibody
- SAP/SH2D1A antibody
- SH2D1A antibody
- XLP antibody
- XLPD antibody
Protein level used designations for SH2D1A
Duncan disease SH2-protein , SH2 domain-containing protein 1A , SLAM associated protein/SH2 domain protein 1A , SLAM-associated protein , T cell signal transduction molecule SAP , T-cell signal transduction molecule SAP , signaling lymphocyte activation molecule-associated protein , signaling lymphocytic activation molecule-associated protein , SH2 domain protein 1A , SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome) , Signaling lymphocytic activation molecule-associated protein , Duncan disease homolog
GENE ID | SPECIES |
---|---|
4068 | Homo sapiens |
501502 | Rattus norvegicus |
613356 | Bos taurus |
574156 | Macaca mulatta |
20400 | Mus musculus |
780420 | Sus scrofa |