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anti-Human MED19 Antibodies:
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Bat Polyclonal MED19 Primary Antibody for WB - ABIN610993
Hernando, Martin-Vasallo, Ghosh, Ghosh, Swaroop, Coca-Prados: Nucleotide sequence of a cDNA for the beta 2 subunit isoform of Na+,K(+)-ATPase from human retina. in Biochimica et biophysica acta 1994
Show all 3 Pubmed References
Cow (Bovine) Polyclonal MED19 Primary Antibody for WB - ABIN2786281
Agaësse, Barbollat-Boutrand, Sulpice, Bhajun, Kharbili, Berthier-Vergnes, Degoul, de la Fouchardière, Berger, Voeltzel, Lamartine, Gidrol, Masse: A large-scale RNAi screen identifies LCMR1 as a critical regulator of Tspan8-mediated melanoma invasion. in Oncogene 2016
Rat (Rattus) Polyclonal MED19 Primary Antibody for WB - ABIN4893986
Rienzo, Casamassimi, Schiano, Grimaldi, Infante, Napoli: Distinct alternative splicing patterns of mediator subunit genes during endothelial progenitor cell differentiation. in Biochimie 2012
supports a role for Med19 as a PolII holoenzyme-embedded "co-factor" that acts together with Hox (show MSH2 Antibodies) proteins through their homeodomains in regulated developmental transcription
LCMR1 modulation was sufficient to positively regulate endogenous Tspan8 (show TSPAN8 Antibodies) expression, with concomitant in vitro phenotypic changes such as loss of melanoma cell-matrix adherence and increase in invasion, and Tspan8 (show TSPAN8 Antibodies) expression promoted tumourigenicity in vivo.
We knocked down the Med19 expression in prostate cancer cell lines LNCaP and PC3 (show PCSK1 Antibodies) by using lentivirus siRNA. Cell proliferation, anchor-independent growth, migration, and invasion were suppressed in Med19 knockdown prostate cancer cells.
Med19 promotes breast cancer cell proliferation and that this effect is associated with regulating CBFA2T3 (show CBFA2T3 Antibodies) and HEB (show TCF12 Antibodies) expression.
FOXD3 (show FOXD3 Antibodies)/miR (show MLXIP Antibodies)-214/MED19 axis is important for the regulation of growth, invasion and metastasis of colorectal cancer
High expression of Med19 is associated with cisplatin resistance in non-small cell lung cancer cells.
Data show that the expression of Mediator of RNA polymerase II transcription subunit 19 (Med19) was increased in Osteosarcoma (OS) samples from patients compared to normal bone tissues.
High Med19 expression is associated with tongue cancer.
Med19 promotes bone metastasis and invasiveness of bladder urothelial carcinoma via bone morphogenetic protein 2 (show BMP2 Antibodies).
Med19 is markedly up-regulated in bladder cancer tissues
LCMR1 suppresses apoptosis in lung cancer cells and this effect is associated with multiple apoptosis-related proteins, including p53 (show TP53 Antibodies), Bax (show BAX Antibodies) and Mcl-1 (show MCL1 Antibodies).
MED19 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003
mediator complex subunit 19
, mediator of RNA polymerase II transcription, subunit 19 homolog (S. cerevisiae)
, mediator of RNA polymerase II transcription, subunit 19 homolog
, mediator of RNA polymerase II transcription subunit 19
, lung cancer metastasis-related protein 1