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FUS low-complexicity phase separates to recruit RNA polymerase II C-terminal domain in vitro.
These findings suggest that N-terminus of Rpb3 selectively inhibits Rpb3-high-expression hepatocellular carcinoma cells proliferation. N-terminus of Rpb3 may be useful in treating patients diagnosed with Rpb3-high-expression hepatocellular carcinoma.
eEF1gamma, in addition to its role in translation elongation complex, is involved in regulating Vimentin gene by contacting both pol II and the Vimentin promoter region and shuttling/nursing the Vimentin mRNA
interaction between RPB3 and ATF4
Rpb3 is a potential nuclear target of insulin-like growth factor binding protein-3
This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21.
DNA-directed RNA polymerase II 33 kDa polypeptide
, DNA-directed RNA polymerase II subunit C
, DNA-directed RNA polymerase II subunit RPB3
, RNA polymerase II subunit 3
, RNA polymerase II subunit B3
, RNA polymerase II 3
, polymerase II polypeptide C
, polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
, DNA directed RNA polymerase II polypeptide C
, polymerase (RNA) II (DNA directed) polypeptide C