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POLH Antibodies

(Polymerase (DNA Directed), eta (POLH))
This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA\; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. [provided by RefSeq, Jul 2008].
POLH antibody  (AA 408-609) POLH antibody  (AA 408-609) POLH antibody (AA 408-609) (ABIN7150247)

POLH Reactivity: Human ELISA, IF, IHC, WB Host: Rabbit Polyclonal unconjugated

POLH antibody POLH antibody POLH antibody (ABIN7252888)

POLH Reactivity: Human, Mouse ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated

POLH antibody  (AA 20-320) POLH antibody  (AA 20-320) POLH antibody (AA 20-320) (ABIN3022621)

POLH Reactivity: Human IF, WB Host: Rabbit Polyclonal unconjugated

POLH Antibodies by Reactivity

Find POLH Antibodies for a variety of species such as anti-Human POLH, anti-Mouse POLH, anti-Rat POLH. The species listed below are among those available. Click on a link to go to the corresponding products.

POLH Antibodies by Application

Find POLH Antibodies validated for a specific application such as WB, IF (cc), IF (p), ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

POLH Antibodies by Host

Find POLH Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

POLH Antibodies by Binding Specificity

Find POLH Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

POLH Antibodies by Clonality

Find available monoclonal or polyclonal POLH Antibodies. Click on a link to go to the corresponding products.

POLH Antibodies by Clone

Find POLH Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

POLH Antibodies by Conjugate

Find POLH Antibodies with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular POLH Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN7150247
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN7252888
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IF, WB
Validations
  • (3)
Cat. No. ABIN3022621
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF, WB
Validations
  • (3)
Cat. No. ABIN7259837
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN6264337
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB
Validations
  • (2)
Cat. No. ABIN3042492
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IC, IF, WB
Validations
  • (2)
Cat. No. ABIN7308184
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IP, WB
Validations
  • (2)
Cat. No. ABIN948279
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, WB
Validations
  • (2)
Cat. No. ABIN519025
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7150250
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7150249
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7150248
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
Cat. No. ABIN1713764
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC (fro), IHC (p), WB
Validations
Cat. No. ABIN1700262
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC (fro), IHC (p), WB
Validations
Cat. No. ABIN1711279
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our POLH Antibodies

Barkley, Palle, Durando, Day, Gurkar, Kakusho, Li, Masai, Vaziri: "c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks." in: Molecular biology of the cell, Vol. 23, Issue 10, pp. 1943-54, (2012) (PubMed).

Day, Palle, Barkley, Kakusho, Zou, Tateishi, Verreault, Masai, Vaziri: "Phosphorylated Rad18 directs DNA polymerase η to sites of stalled replication." in: The Journal of cell biology, Vol. 191, Issue 5, pp. 953-66, (2010) (PubMed).

Parker, Bielen, Dikic, Ulrich: "Contributions of ubiquitin- and PCNA-binding domains to the activity of Polymerase eta in Saccharomyces cerevisiae." in: Nucleic acids research, Vol. 35, Issue 3, pp. 881-9, (2007) (PubMed).

Skoneczna, McIntyre, Skoneczny, Policinska, Sledziewska-Gojska: "Polymerase eta is a short-lived, proteasomally degraded protein that is temporarily stabilized following UV irradiation in Saccharomyces cerevisiae." in: Journal of molecular biology, Vol. 366, Issue 4, pp. 1074-86, (2007) (PubMed).

Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).

Glick, Vigna, Loeb: "Mutations in human DNA polymerase eta motif II alter bypass of DNA lesions." in: The EMBO journal, Vol. 20, Issue 24, pp. 7303-12, (2001) (PubMed).

Yuasa, Masutani, Eki, Hanaoka: "Genomic structure, chromosomal localization and identification of mutations in the xeroderma pigmentosum variant (XPV) gene." in: Oncogene, Vol. 19, Issue 41, pp. 4721-8, (2000) (PubMed).

Masutani, Kusumoto, Yamada, Dohmae, Yokoi, Yuasa, Araki, Iwai, Takio, Hanaoka: "The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta." in: Nature, Vol. 399, Issue 6737, pp. 700-4, (1999) (PubMed).

Johnson, Kondratick, Prakash, Prakash: "hRAD30 mutations in the variant form of xeroderma pigmentosum." in: Science (New York, N.Y.), Vol. 285, Issue 5425, pp. 263-5, (1999) (PubMed).

Aliases for POLH Antibodies

polymerase (DNA directed), eta S homeolog (polh.S) Antibodies
DNA polymerase eta (POLH) Antibodies
polymerase (DNA directed), eta (polh) Antibodies
DNA polymerase eta (Tb10.70.6190) Antibodies
putative DNA polymerase eta (LINJ_21_0690) Antibodies
polymerase (DNA directed), eta (Polh) Antibodies
DNA polymerase eta (LOC100443019) Antibodies
DNA polymerase eta (polh) Antibodies
DNA polymerase eta (Polh) Antibodies
polymerase (DNA directed), eta (RAD 30 related) (Polh) Antibodies
fc50a12 Antibodies
POLH Antibodies
RAD30 Antibodies
RAD30A Antibodies
wu:fc50a12 Antibodies
XP-V Antibodies
XPV Antibodies
zgc:136881 Antibodies
zgc:152642 Antibodies
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