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POLG Antibodies

(Polymerase (DNA Directed), gamma (POLG))
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
POLG antibody  (C-Term) POLG antibody  (C-Term) POLG antibody (C-Term) (ABIN2854742)

POLG Reactivity: Human, Rat ICC, IF, IP, IHC (p), WB Host: Rabbit Polyclonal unconjugated

POLG antibody  (AA 1101-1239) POLG antibody  (AA 1101-1239) POLG antibody (AA 1101-1239) (ABIN1714946)

POLG Reactivity: Human, Mouse, Rat ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated

POLG antibody  (Internal Region) POLG antibody  (Internal Region) POLG antibody (Internal Region) (ABIN6264336)

POLG Reactivity: Human, Mouse, Rat ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated

POLG Antibodies by Reactivity

Find POLG Antibodies for a variety of species such as anti-Human POLG, anti-Mouse POLG, anti-Rat POLG. The species listed below are among those available. Click on a link to go to the corresponding products.

POLG Antibodies by Application

Find POLG Antibodies validated for a specific application such as WB, ELISA, IF (cc), IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

POLG Antibodies by Host

Find POLG Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

POLG Antibodies by Binding Specificity

Find POLG Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

POLG Antibodies by Clonality

Find available monoclonal or polyclonal POLG Antibodies. Click on a link to go to the corresponding products.

POLG Antibodies by Conjugate

Find POLG Antibodies with a specific conjugate such as Biotin, FITC, Alexa Fluor 750. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular POLG Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application ICC, IF, IP, IHC (p), WB
Validations
  • (5)
Cat. No. ABIN2854742
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (1)
  • (2)
Cat. No. ABIN1714946
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN6264336
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application FACS, IF, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN5534169
Quantity 400 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN2783430
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN7150263
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF (cc), IF (p)
Validations
  • (1)
Cat. No. ABIN1696002
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Hamster, Human, Mouse, Pig, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6747379
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN928250
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ICC, IF, IHC (p), WB
Validations
  • (1)
Cat. No. ABIN1738189
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7150266
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7150265
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7150264
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, ICC, IHC (fro), IHC (p), WB
Validations
Cat. No. ABIN6998387
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC (fro), IHC (p), WB
Validations
Cat. No. ABIN1701444
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our POLG Antibodies

Chen, Zhao, Cai, Sun, Hu, Huang, Kong, Kong: "The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways." in: Redox biology, Vol. 12, pp. 987-1003, (2017) (PubMed).

Prasad, Çağlayan, Dai, Nadalutti, Zhao, Gassman, Janoshazi, Stefanick, Horton, Krasich, Longley, Copeland, Griffith, Wilson: "DNA polymerase β: A missing link of the base excision repair machinery in mammalian mitochondria." in: DNA repair, Vol. 60, pp. 77-88, (2017) (PubMed).

Li, Guo, Ying, Chen, Yang, Chen, Long, Qin, Pei, Liu: "Valproic acid-induced hepatotoxicity in Alpers syndrome is associated with mitochondrial permeability transition pore opening-dependent apoptotic sensitivity in an induced pluripotent stem cell model." in: Hepatology (Baltimore, Md.), Vol. 61, Issue 5, pp. 1730-9, (2015) (PubMed).

Mancini, Roncaglia, Brussino, Stevanin, Lo Buono, Krmac, Maltecca, Gazzano, Bartoletti Stella, Calvaruso, Iommarini, Cagnoli, Forlani, Le Ber, Durr, Brice, Ghigo, Casari, Porcelli, Funaro, Gasparre et al.: "Genome-wide expression profiling and functional characterization of SCA28 lymphoblastoid cell lines reveal impairment in cell growth and activation of apoptotic pathways. ..." in: BMC medical genomics, Vol. 6, pp. 22, (2013) (PubMed).

Roos, Macao, Fusté, Lindberg, Jemt, Holme, Moslemi, Oldfors, Falkenberg: "Subnormal levels of POLγA cause inefficient initiation of light-strand DNA synthesis and lead to mitochondrial DNA deletions and progressive external ophthalmoplegia [corrected]." in: Human molecular genetics, Vol. 22, Issue 12, pp. 2411-22, (2013) (PubMed).

Wu, Li, Zhang, Wu, Huang, Chen: "Mitochondrial DNA base excision repair and mitochondrial DNA mutation in human hepatic HuH-7 cells exposed to stavudine." in: Mutation research, Vol. 664, Issue 1-2, pp. 28-38, (2009) (PubMed).

Aliases for POLG Antibodies

polymerase (DNA) gamma, catalytic subunit L homeolog (polg.L) Antibodies
DNA polymerase gamma, catalytic subunit (Polg) Antibodies
DNA polymerase gamma, catalytic subunit (POLG) Antibodies
polymerase (DNA directed), gamma (POLG) Antibodies
polymerase (DNA directed), gamma (polg) Antibodies
polymerase (DNA directed), gamma (Polg) Antibodies
AA409516 Antibodies
MDP1 Antibodies
MIRAS Antibodies
MTDPS4A Antibodies
MTDPS4B Antibodies
PEO Antibodies
POLG Antibodies
POLG1 Antibodies
POLGA Antibodies
PolgA Antibodies
SANDO Antibodies
SCAE Antibodies
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