Browse our anti-CREM (CREM) Antibodies

Human CAMP Responsive Element Modulator (CREM) interaction partners

1. this study shows an eventually involvement of CREM gene in the development of T1D pathology in Tunisian families. These facts are consistent with a major role for transcription factor genes involved in the immune pathways in the control of autoimmunity.

2. Data indicate a role for inducible cyclic AMP early repressor (ICER) in G1 checkpoint regulation in hematopoietic stem cells (HSCs).

3. Report a distinct group of myxoid mesenchymal neoplasms occurring in children or young adults with a predilection for intracranial locations with EWSR1 (show EWSR1 Antibodies)-AFT1/CREB1 (show CREB1 Antibodies)/CREM fusions.

4. Study provides evidence that increased Set1 (show SETD1A Antibodies) binding at the promoter induces aberrant epigenetic alterations and up-regulates CREMA in systemic lupus erythematosus.

5. These findings indicated that the polymorphisms of CREM gene were associated with nonobstructive azoospermia in the Chinese population and low CREM expression might be involved in the pathogenesis of spermatogenesis maturation arrest.

6. In Alzheimer's brain, we found an increased cellular expression of CREM in dentate gyrus neurons as compared to normal aging brains.

7. Data suggest ICER/CREM plays seminal role in down-regulation of expression/secretion of insulin (show INS Antibodies) by pancreatic beta-cell as an adaptive response to factors that promote diabetes; inappropriate induction of ICER leads to beta-cell dysfunction. [REVIEW]

8. CaMK4 (show CAMK4 Antibodies)-dependent activation of AKT (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) and CREM-alpha underlies autoimmunity-associated Th17 imbalance.

9. CREMalpha orchestrates epigenetic remodeling of the CD8A (show CD8A Antibodies),B through the recruitment of DNA methyltransferase (show DNMT1 Antibodies) (DNMT (show DNMT1 Antibodies)) 3a and histone methyltransferase G9a (show EHMT2 Antibodies).

10. Data suggest that cyclic AMP (show APRT Antibodies) response element modulator-1 (CREM-1) might play an important role in the regulation of tumor metastasis and invasion and serve as a tumor suppressor in esophageal squamous cell carcinoma (ESCC).

Cow (Bovine) CAMP Responsive Element Modulator (CREM) interaction partners

1. results are consistent with the suggestions that cAMP responsive element modulator variants are involved in spermiogenesis in the testes of Japanese Black bulls

Mouse (Murine) CAMP Responsive Element Modulator (CREM) interaction partners

1. Deficiency in ICER elevated binding of NF-kappaB (show NFKB1 Antibodies) to promoters of pro-inflammatory genes and their subsequent gene expression. Mice deficient in ICER were hypersensitive to LPS (show TLR4 Antibodies)-induced endotoxic shock and showed propagated inflammation.

2. The transcription factor CREM was found to be important in the regulation of cardiotoxicity-associated genes.

3. Our results demonstrate that overexpression of CREMalpha in T cells changes the inflammatory milieu, attenuating initiation and progression of CLD (show LMF1 Antibodies).

4. the role of ICER in ovarian function, was investigated.

5. Phosphorylated Tssk4 (show TSSK4 Antibodies) might participate in testis genes expressions by phosphorylating Crem at Ser (show SIGLEC1 Antibodies)-117.

6. the signaling pathways mediating GnRH activation of CREB and ICER are distinct, contributing to the decoding of the pulsatile GnRH to regulate FSHbeta expression.

7. Crem(-/-) mice exhibited increased proliferation of primary aortic VSMCs along with upregulation of PDGF (show PDGFA Antibodies) signaling.

8. These data identify ICER as a redundant mediator of Treg cells and cAMP action on Teff cells and suggest that Epac (show RAPGEF3 Antibodies) may function as an alternative effector to promote cAMP-dependent Teff cell suppression.

9. CaMK4 (show CAMK4 Antibodies)-dependent activation of AKT (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) and CREM-alpha underlies autoimmunity-associated Th17 imbalance.

10. CREMalpha orchestrates epigenetic remodeling of the CD8A (show CD8A Antibodies),B through the recruitment of DNA methyltransferase (show DNMT1 Antibodies) (DNMT (show DNMT1 Antibodies)) 3a and histone methyltransferase G9a (show EHMT2 Antibodies).