Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) Proteins

(Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))

Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.

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RIC8A Protein (AA 1-531) (His tag)

custom-made RIC8A Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant RIC8A Protein, UniprotID Q9NPQ8

3 images

Catalog No. ABIN7555232

Details

RIC8A Protein (AA 1-530) (His tag)

custom-made RIC8A Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Ric8a Protein, UniprotID Q3TIR3

3 images

Catalog No. ABIN7563667

Details

RIC8A Protein (AA 1-530) (Strep Tag)

custom-made RIC8A Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Catalog No. ABIN3134973

Details

RIC8A Protein (AA 1-531) (Strep Tag)

custom-made RIC8A Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Catalog No. ABIN3095036