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GEMIN5 Proteins

(Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].

3 results

custom-made GEMIN5 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7564451
 
custom-made GEMIN5 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7553999
 
GEMIN5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Pubmed 1 reference
Catalog No. ABIN2721790
 
  • Type Protein
    • Protein
  • Application
    • Antibody Production (AbP)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • HEK-293 Cells
  • Binding Specificity
    • AA 1-1502
    • AA 1-1508
  • Conjugate
    • His tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • OriGene

Latest Publications for our GEMIN5 Proteins

Francisco-Velilla, Fernandez-Chamorro, Ramajo, Martinez-Salas: "The RNA-binding protein Gemin5 binds directly to the ribosome and regulates global translation." in: Nucleic acids research, Vol. 44, Issue 17, pp. 8335-51, (2016) (PubMed).

Aliases for GEMIN5 Proteins

gem nuclear organelle associated protein 5 (GEMIN5) Proteins
gem nuclear organelle associated protein 5 (Gemin5) Proteins
gem (nuclear organelle) associated protein 5 (Gemin5) Proteins
AA407055 Proteins
AA407208 Proteins
AI451603 Proteins
BB194447 Proteins
C330013N08 Proteins
GEMIN-5 Proteins
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