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The results presented in this work indicate a close functional interaction between NIP7 and FTSJ3 (show FTSJ3 Proteins) during pre-rRNA processing and show that FTSJ3 (show FTSJ3 Proteins) participates in ribosome synthesis in human cells.
Downregulation of NIP7 affects pre-rRNA processing, causing an imbalance of the 40S/60S subunit ratio.
SBDS (show SBDS Proteins) is found in complexes containing the human Nip7 ortholog.
Study is the first to establish the primary foundation for further research on the swine NIP7 gene (AY864609).
Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly (By similarity).
60S ribosome subunit biogenesis protein NIP7 homolog
, nuclear import 7 homolog
, Saccharomyces cerevisiae Nip7p homolog
, nuclear import 7
, PUA protein