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anti-Human ATP2B1 Antibodies:
anti-Rat (Rattus) ATP2B1 Antibodies:
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Amphibian Monoclonal ATP2B1 Primary Antibody for FACS, ICC - ABIN152735
Krizaj, Liu, Copenhagen: Expression of calcium transporters in the retina of the tiger salamander (Ambystoma tigrinum). in The Journal of comparative neurology 2004
Show all 7 Pubmed References
Human Polyclonal ATP2B1 Primary Antibody for ELISA, WB - ABIN4346333
Benetti, Mičetić, Carsughi, Spinozzi, Bubacco, Beltramini: Insights into the oligomerization process of the C-terminal domain of human plasma membrane Ca²+-ATPase. in Archives of biochemistry and biophysics 2011
Adding pure bovine MMP-2 (show MMP2 Antibodies) to the smooth muscle membrane suspension causes an increase in Ca(2+)-ATPase (show CA-P60A Antibodies) activity, but the pretreatment with TIMP-2 (show TIMP2 Antibodies) inhibits the increase in the enzyme activity
To demonstrate the subcellular localization and regulation of bovine sperm PMCA, cell fractionation, enzyme activity determination and Western blotting studies of PMCA in spermatozoa removed from the cauda epididymidis of bull, was performed.
people with the major allele of ATP2B1 rs17249754 are susceptible to hypertension especially in low intake of Ca and high ratio of Na and K
Crossover analysis and stratified analysis indicated that BMI has a major effect on the development of hypertension, while ATP2B1 variants have a minor effect
Excessive sodium intake significantly modified the risk of developing Hypertension associated with ATP2B1 rs17249754 genetic trait. Homozygote carriers may be at higher risk of hypertension, when they consume excessive sodium intake.
Data show that plasma membrane Ca(2+)-ATPase (show ATP2B2 Antibodies) (PMCA) was associated with tubulin (show TUBB Antibodies) in normotensive and hypertensive erythrocytes.
rs11105378 near ATP2B1 was associated with increased systolic and diastolic blood pressure in a Chinese population.
ATP2B1 rs12817819 A allele is associated with increased risk for drug resistant hypertension.
While PMCA1b has a housekeeping function in colon cancer cells, PMCA4b (show ATP2B4 Antibodies) participates in the reorganization of the calcium signaling machinery during cell differentiation.
Report that ATP2B1 rs2681472 is associated with early-onset preeclampsia in Northern Han Chinese women.
An increase of phosphatidylcholine (show SGMS2 Antibodies)/detergent molar ratio leads to a biphasic behavior of the PMCA Ca2+-ATPase activity, whose maximum depends on phosphatidylcholine (show SGMS2 Antibodies) characteristics.
The present study confirmed the significant association of ATP2B1 rs17249754 with risk of hypertension among Chinese children.
Purified plasma membrane Ca2+ ATPase was able to hydrolyze ATP at a very low rate in the absence of Ca2 (show CA2 Antibodies)+.
results suggest that the activating mechanism of ethanol may involve opening an autoinhibitory domain located close to the calmodulin binding domain
ceramide activates plasma membrane Ca2+-ATPase from kidney-promixal tubule cells with protein kinase A as an intermediate
These results suggest that renal PMCA1 has a role as one of the molecules involved in angiotensin II-induced hypertension and kidney injury.
PMCA1 is required for maintaining atrial Ca(2 (show CA2 Antibodies)+) homeostasis and electrical stability.
Decreased expression of PMCA1 is associated with increased blood pressure when combined with advancing age.
Deletion of the Pmca1 in the intestine is associated with reduced growth and bone mineralization, and a failure to up-regulate calcium absorption in response to 1alpha,25(OH)2D3.
decreased ATP2B1 gene expression is associated with impaired endothelial NOS (show NOS3 Antibodies) activity and nitric oxide production, and the ATP2B1 gene plays a crucial role in the regulation of blood pressure
ATP2B1 is the causative gene in the blood pressure-associated 12q21 locus; ATP2B1 expression in the vessel influences blood pressure
ATP2B1 plays important roles in the regulation of blood pressure through alteration of calcium handling and vasoconstriction in vascular smooth muscle cells.
Cav1.4alpha1 (show CACNA1F Antibodies) is required for proper targeting of the presynaptic PMCA1 complex in retinal photoreceptors.
the decapacitation mechanism of the SVA might target membrane sphingolipid SPM (show NPC1 Antibodies) and regulate PMCA activity to lower [Ca(2 (show CA2 Antibodies)+)](i), thereby decreasing the [cAMP](i) level and preventing sperm pre-capacitation.
Plasma membrane Ca2+-ATPase and NCX1 Na+/Ca2+ exchanger (show SLC8A1 Antibodies) expression in distal convoluted tubule cells mediate calcium efflux.
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified.
plasma membrane calcium ATPase 1
, plasma membrane calcium-transporting ATPase 1
, plasma membrane calcium pump
, ATPase, Ca++ transporting, plasma membrane 1
, plasma membrane calcium-transporting ATPase 1-like
, plasma membrane calcium ATPase
, plasma membrane Ca2+ pump (PMCA1b)
, Ca2+/Mg2+ ATPase