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SAFB Products

(Scaffold Attachment Factor B (SAFB))

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This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011].

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Featured SAFB Categories

SAFB Antibodies

High quality antibodies with extensive validation data.

SAFB Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SAFB Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, IHC
Validations
  • (7)
Cat. No. ABIN7263975
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC
Validations
  • (14)
Cat. No. ABIN6147357
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (6)
Cat. No. ABIN2855048
Quantity 100 μL
Datasheet Datasheet

Recommended SAFB ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6207511
Quantity 96 tests
Datasheet Datasheet

Recommended SAFB Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319112
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095224
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3131089
Quantity 1 mg
Datasheet Datasheet

Synonyms and alternative names related to SAFB

scaffold attachment factor B (SAFB), scaffold attachment factor B (Safb), scaffold attachment factor B (safb), scaffold attachment factor B S homeolog (safb.S), SAFB-like transcription modulator (LOC5570070), scaffold attachment factor B (CpipJ_CPIJ017179), Scaffold attachment factor B (Bm1_49330), scaffold attachment factor B (LOAG_00080), 3110021E02Rik, 5330423C17Rik, AU018122, D18386, E130307D12, HAP, HET, SAF-B1, SAFB, SAFB1, SAFB2, wu:fb40a03, wu:fd42g06, zgc:55387

Protein level used designations for SAFB

  • HSP27 ERE-TATA-binding protein
  • HSP27 estrogen response element-TATA box-binding protein
  • Hsp27 ERE-TATA binding protein
  • SAB-B1
  • SAF-B
  • glutathione S-transferase fusion protein
  • heat-shock protein (HSP27) estrogen response element and TATA box-binding protein
  • scaffold attachment factor B1
  • SAF-B1
  • scaffold attachment factor B2
  • scaffold attachment factor B
  • scaffold attachment factor b
  • Scaffold attachment factor B
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