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Selenoprotein F Protein (SELENOF) (S96C) (His tag)

SELENOF Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95% by SDS-PAGE SDS
Catalog No. ABIN7596434
  • Target
    Selenoprotein F (SELENOF)
    Protein Type
    Recombinant
    Protein Characteristics
    S96C
    Origin
    Human
    Source
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Selenoprotein F protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MGSVSAFGAE FSSEACRELG FSSNLLCSSC DLLGQFNLLQ LDPDCRGCCQ EEAQFETKKL YAGAILEVCG CKLGRFPQVQ AFVRSDKPKL FRGLQIKYVR GSDPVLKLLD DNGNIAEELS ILKWNTDSVE EFLSEKLERI
    Purity
    > 95% by SDS-PAGE
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • Target
    Selenoprotein F (SELENOF)
    Alternative Name
    Seleno F (SC96C)
    Background
    SEP15 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the uGA codon that normally signals translation termination. The 3' uTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of uGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Recombinant human SEP15 (SC96C) protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
    Molecular Weight
    17.7 kDa (160aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_004252
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